The past decade has seen tremendous developments in novel cancer therapies through the
targeting of tumor-cell-intrinsic pathways whose activity is linked to genetic alterations and …

Virus-like particles (VLPs) have been shown to be strong activators of dendritic cells (DCs).
DCs are the most potent antigen presenting cells (APCs) and their activation prompts the …

B and T lymphocytes are the mediators of immunity, but their function is under the control of
dendritic cells. Dendritic cells in the periphery capture and process antigens, express …

Dendritic cells (DCs) are antigen-presenting cells with a unique ability to induce primary
immune responses. DCs capture and transfer information from the outside world to the cells …

Dendritic cells are rare haematopoietic cells that reside in a number of organs and tissues.
By capturing, processing and presenting antigens to T cells, dendritic cells are essential for …

The intestinal mucosa is a physiological barrier for most microbes, including both
commensal bacteria and invading pathogens. Under homeostatic conditions …

CD40 is a cell surface receptor that belongs to the tumor necrosis factor‐R (TNF‐R) family,
and that was first identified and functionally characterized on B lymphocytes. Its critical role …

Members of the tumor necrosis factor (TNF) family induce pleiotropic biological responses,
including cell growth, differentiation, and even death. Here we describe a novel member of …

Dendritic cells (DCs) initiate and control immune responses. Plasmacytoid DCs (pDCs)
represent a unique DC subset able to promptly release large amounts of type I interferon …

Dendritic cells (DCs) are important in regulating both immunity and tolerance. Hence, we
hypothesized that systemic lupus erythematosus (SLE), an autoimmune disease …