Flexible, penetrating brain probes enabled by advances in polymer microfabrication
A Weltman, J Yoo, E Meng - Micromachines, 2016 - mdpi.com
The acquisition of high-fidelity, long-term neural recordings in vivo is critically important to
advance neuroscience and brain–machine interfaces. For decades, rigid materials such as …
advance neuroscience and brain–machine interfaces. For decades, rigid materials such as …
Close-packed silicon microelectrodes for scalable spatially oversampled neural recording
J Scholvin, JP Kinney, JG Bernstein… - IEEE Transactions …, 2015 - ieeexplore.ieee.org
Objective: Neural recording electrodes are important tools for understanding neural codes
and brain dynamics. Neural electrodes that are closely packed, such as in tetrodes, enable …
and brain dynamics. Neural electrodes that are closely packed, such as in tetrodes, enable …
Demonstration of cortical recording using novel flexible polymer neural probes
We present the fabrication, characterization, use in cortical recording and histological results
of a flexible implantable neural probe. The microfabricated device is implemented in …
of a flexible implantable neural probe. The microfabricated device is implemented in …
Chronic neural recording with probes of subcellular cross-section using 0.06 mm² dissolving microneedles as insertion device
F Ceyssens, MB Carmona, D Kil, M Deprez… - Sensors and Actuators B …, 2019 - Elsevier
Ultra-flexible electrode arrays with a cross-sectional area of only a few μm² show great
promise for long-term, high resolution neural interfacing without detrimental scar tissue …
promise for long-term, high resolution neural interfacing without detrimental scar tissue …
Computational assessment of neural probe and brain tissue interface under transient motion
M Polanco, S Bawab, H Yoon - Biosensors, 2016 - mdpi.com
The functional longevity of a neural probe is dependent upon its ability to minimize injury risk
during the insertion and recording period in vivo, which could be related to motion-related …
during the insertion and recording period in vivo, which could be related to motion-related …
Ultrastructural analysis of neuroimplant-parenchyma interfaces uncover remarkable neuroregeneration along-with barriers that limit the implant electrophysiological …
Despite increasing use of in vivo multielectrode array (MEA) implants for basic research and
medical applications, the critical structural interfaces formed between the implants and the …
medical applications, the critical structural interfaces formed between the implants and the …
Immunohistological and ultrastructural study of the inflammatory response to perforated polyimide cortical implants: mechanisms underlying deterioration of …
The deterioration of field potential (FP) recording quality and yield by in vivo multielectrode
arrays (MEA) within days to weeks of implantation severely limits progress in basic and …
arrays (MEA) within days to weeks of implantation severely limits progress in basic and …
flexLiTE: flexible micro-LED integrated optoelectrodes for long-term chronic deep-brain studies
Understanding complex neuronal circuitry and its functions of a living organism requires a
specialized tool which is capable of recording a large ensemble of neuronal signals at …
specialized tool which is capable of recording a large ensemble of neuronal signals at …
Stiffness‐Changing of Polymer Nanocomposites with Cellulose Nanocrystals and Polymeric Dispersant
Abstract Bio‐inspired, water‐responsive, mechanically adaptive nanocomposites are
reported based on cellulose nanocrystals (CNCs), poly (ethylene oxide‐co …
reported based on cellulose nanocrystals (CNCs), poly (ethylene oxide‐co …
Controlled release drug coatings on flexible neural probes
We present the development, characterization and in vivo validation of a novel drug eluting
coating that has been applied to flexible neural probes. The coating consists of drug eluting …
coating that has been applied to flexible neural probes. The coating consists of drug eluting …