X-ray-based 3D virtual histology—Adding the next dimension to histological analysis

J Albers, S Pacilé, MA Markus, M Wiart… - Molecular Imaging and …, 2018 - Springer
Histology and immunohistochemistry of thin tissue sections have been the standard
diagnostic procedure in many diseases for decades. This method is highly specific for …

Neurons on tape: Automated Tape Collecting Ultramicrotomy-mediated volume EM for targeting neuropathology

G Kislinger, C Niemann, L Rodriguez, H Jiang… - Methods in cell …, 2023 - Elsevier
In this chapter, we review Automated Tape Collecting Ultramicrotomy (ATUM), which, among
other array tomography methods, substantially simplified large-scale volume electron …

Host autophagy mediates organ wasting and nutrient mobilization for tumor growth

R Khezri, P Holland, TA Schoborg, I Abramovich… - The EMBO …, 2021 - embopress.org
During tumor growth—when nutrient and anabolic demands are high—autophagy supports
tumor metabolism and growth through lysosomal organelle turnover and nutrient recycling …

Micro-computed tomography as a platform for exploring Drosophila development

TA Schoborg, SL Smith, LN Smith, HD Morris… - …, 2019 - journals.biologists.com
Understanding how events at the molecular and cellular scales contribute to tissue form and
function is key to uncovering the mechanisms driving animal development, physiology and …

Visualization of the membranous labyrinth and nerve fiber pathways in human and animal inner ears using microCT imaging

R Glueckert, L Johnson Chacko… - Frontiers in …, 2018 - frontiersin.org
Design and implantation of bionic implants for restoring impaired hair cell function relies on
accurate knowledge about the microanatomy and nerve fiber pathways of the human inner …

Size and specimen-dependent strategy for x-ray micro-ct and tem correlative analysis of nervous system samples

P Parlanti, V Cappello, F Brun, G Tromba, R Rigolio… - Scientific reports, 2017 - nature.com
Correlative approaches are a powerful tool in the investigation of biological samples, but
require specific preparation procedures to maintain the strength of the employed methods …

An optimized workflow for microCT imaging of formalin‐fixed and paraffin‐embedded (FFPE) early equine embryos

S Handschuh, CTC Okada, I Walter… - Anatomia, histologia …, 2022 - Wiley Online Library
Here, we describe a workflow for high‐detail microCT imaging of formalin‐fixed and paraffin‐
embedded (FFPE) equine embryos recovered on Day 34 of pregnancy (E34), a period just …

Microscopes, tools, probes, and protocols: A guide in the route of correlative microscopy for biomedical investigation

P Parlanti, V Cappello - Micron, 2022 - Elsevier
In the last decades, the advancements of microscopes technology, together with the
development of new imaging approaches, are trying to address some biological questions …

Comparative hard x-ray tomography for virtual histology of zebrafish larva, human tooth cementum, and porcine nerve

A Migga, G Schulz, G Rodgers… - Journal of Medical …, 2022 - spiedigitallibrary.org
Purpose: Synchrotron radiation-based tomography yields microanatomical features in
human and animal tissues without physical slicing. Recent advances in instrumentation …

Recent developments in 3-D reconstruction and stereology to study the pulmonary vasculature

C Mühlfeld, C Wrede, L Knudsen… - … of Physiology-Lung …, 2018 - journals.physiology.org
Alterations of the pulmonary vasculature are an important feature of human lung diseases
such as chronic obstructive pulmonary disease, pulmonary hypertension, and …