Spatial gene expression analysis reveals characteristic gene expression patterns of de novo neuroendocrine prostate cancer coexisting with androgen receptor …

R Watanabe, N Miura, M Kurata, R Kitazawa… - International Journal of …, 2023 - mdpi.com
Neuroendocrine prostate carcinoma (NEPC) accounts for less than 1% of prostate
neoplasms and has extremely poorer prognosis than the typical androgen receptor pathway …

[HTML][HTML] Integrated analysis of single-cell and bulk transcriptomics develops a robust neuroendocrine cell-intrinsic signature to predict prostate cancer progression

T Zhang, F Zhao, Y Lin, M Liu, H Zhou, F Cui, Y Jin… - Theranostics, 2024 - ncbi.nlm.nih.gov
Neuroendocrine prostate cancer (NEPC) typically implies severe lethality and limited
treatment options. The precise identification of NEPC cells holds paramount significance for …

Unraveling molecular characteristics and tumor microenvironment dynamics of neuroendocrine prostate cancer

D Heimdörfer, N Artamonova, Z Culig… - Journal of Cancer …, 2024 - Springer
Prostate cancer (PCa) is the most prevalent malignancy and the second leading cause of
cancer-related deaths among men. While adenocarcinoma of the prostate (adeno-PCa) is …

A new tumorgraft panel to accelerate precision medicine in prostate cancer

C Béraud, N Bidan, M Lassalle, H Lang… - Frontiers in …, 2023 - frontiersin.org
Background Despite the significant advances in the management of advanced prostate
cancer (PCa), metastatic PCa is currently considered incurable. For further investigations in …

[HTML][HTML] Pan-cancer analysis of CTNNB1 with potential as a therapeutic target for human tumorigenesis

M AmeliMojarad, M AmeliMojarad, X Cui - Informatics in Medicine …, 2023 - Elsevier
Background Despite the different studies on the oncogenic role of Catenin Beta 1 (CTNNB1)
and its association with cancer pathogenesis, there is no pan-cancer study to clarify its …

Psychoneuroimmunology and Cancer: The New Insights for Improving Immune Activation and Quality of Life in Cancer Patients

S Gezici - … : Volume 2: Interdisciplinary Approaches to Diseases, 2025 - Springer
Psychoneuroimmunology (PNI) is a growing field of research that focuses on the
relationship between psychological factors, the nervous system, the endocrine system, and …

Investigating Carcinoid Tumor Oncogenesis through the lens of Developmental Dynamics involved in Small Intestinal Neuroendocrine Cells

O Shafi, MD Yaqub - 2024 - researchsquare.com
Background: Carcinoid tumors from small intestinal Neuroendocrine Cells (SI-NECs)
present clinical challenges with increasing incidence. Investigating the genetic architecture …

KDM4A promotes NEPC progression through regulation of MYC expression

CSL Mak, M Zhu, X Liang, F Wang, AG Hoang, X Song… - bioRxiv, 2022 - biorxiv.org
Purpose Despite advancement in treatment, prostate cancer (PCa) remains the second
leading cause of death among men. Neuroendocrine prostate cancer (NEPC) represents …