Fungal extracellular vesicles are involved in intraspecies intracellular communication

TA Bitencourt, O Hatanaka, AM Pessoni, MS Freitas… - MBio, 2022 - Am Soc Microbiol
Fungal infections are associated with high mortality rates in humans. The risk of fungal
diseases creates the urgent need to broaden the knowledge base regarding their …

Proteomic Analysis of Paracoccidioides brasiliensis During Infection of Alveolar Macrophages Primed or Not by Interferon-Gamma

EGA Chaves, JA Parente-Rocha, LC Baeza… - Frontiers in …, 2019 - frontiersin.org
Although members of the Paracoccidioides complex are not obligate intracellular
pathogens, they present the ability to survive and multiply inside epithelial cells and …

Galectin-3 inhibits Paracoccidioides brasiliensis growth and impacts paracoccidioidomycosis through multiple mechanisms

O Hatanaka, CP Rezende, P Moreno… - MSphere, 2019 - Am Soc Microbiol
The thermodimorphic pathogenic fungi Paracoccidioides brasiliensis and Paracoccidioides
lutzii are the etiologic causes of paracoccidioidomycosis (PCM), the most prevalent systemic …

Role of paracoccin on Paracoccidioides brasiliensis virulence and susceptibility to antifungal drugs in the Galleria mellonella larvae model

N de Souza Pitangui, FF Fernandes… - Virulence, 2023 - Taylor & Francis
Paracoccin (PCN), a Paracoccidioides brasiliensis glycoprotein, has been reported to play
roles in fungal biology and paracoccidioidomycosis pathogenesis. Lectin and chitinase …

Paracoccin distribution supports its role in Paracoccidioides brasiliensis growth and dimorphic transformation

AF Oliveira, FF Fernandes, VS Mariano, F Almeida… - Plos one, 2017 - journals.plos.org
Paracoccidioides brasiliensis yeast was reported to express paracoccin, a GlcNAc-binding
protein that displays N-acetyl-β-d-glucosaminidase (NAGase) activity. Highly specific anti …

Decyl Gallate as a Possible Inhibitor of N-Glycosylation Process in Paracoccidioides lutzii.

ESACA De Paula, HC De Oliveira… - Antimicrobial Agents …, 2019 - europepmc.org
The available antifungal therapeutic arsenal is limited. The search for alternative drugs with
fewer side effects and new targets remains a major challenge. Decyl gallate (G14) is a …

Paracoccin impacts on Paracoccidioides brasiliensis virulence and susceptibility to antifungal drugs by modifying the expression of genes related to remodeling of the …

NS Pitangui, FF Fernandes, TA da Silva, RA Gonçales… - bioRxiv, 2022 - biorxiv.org
The study of the paracoccin lectin (PCN) has provided knowledge about its role in the
biology of Paracoccidioides brasiliensis and in the pathogenesis of paracoccidioidomycosis …

[HTML][HTML] Decyl Gallate as a Possible Inhibitor of N-Glycosylation Process in Paracoccidioides lutzii

HC de Oliveira, L Scorzoni, CM Marcos… - Antimicrobial Agents …, 2019 - ncbi.nlm.nih.gov
The available antifungal therapeutic arsenal is limited. The search for alternative drugs with
fewer side effects and new targets remains a major challenge. Decyl gallate (G14) is a …

Identificação de metabólitos secundários presentes em vesículas extracelulares de Candida albicans durante estresse oxidativo

GES Trentin - 2022 - teses.usp.br
Candida albicans é um fungo comensal em humanos saudáveis, podendo causar infecção
em alguns indivíduos por meio da secreção de diversos fatores de virulência. O sucesso do …

Decyl Gallate as a Possible Inhibitor of N-Glycosylation Process in Paracoccidioides lutzii

ACA de Paula e Silva, HC de Oliveira… - Antimicrobial Agents …, 2019 - Am Soc Microbiol
The available antifungal therapeutic arsenal is limited. The search for alternative drugs with
fewer side effects and new targets remains a major challenge. Decyl gallate (G14) is a …