Statins are effective cholesterol-lowering drugs that reduce the risk of cardiovascular
disease events (heart attacks, strokes, and the need for arterial revascularisation). Adverse …

Background: Statins are the most commonly prescribed agents for hypercholesterolemia
because of their efficacy and tolerability. As the number of patients in need of statin therapy …

Importance The American College of Cardiology and the American Heart Association
(ACC/AHA) cholesterol treatment guidelines have wide-scale implications for treating adults …

Objective To quantify an association between acute kidney injury and use of high potency
statins versus low potency statins. Design Retrospective observational analysis of …

Purpose To assess the cost-effectiveness and clinical efficacy of AI-assisted abdominal CT-
based opportunistic screening for atherosclerotic cardiovascular (CV) disease, osteoporosis …

The 3-hydroxy-3-methylglutaryl coenzyme A (HMG-CoA) reductase inhibitors, or statin
drugs, have been studied in numerous controlled human research trials involving hundreds …

Objectives: We sought to assess the relationship between the magnitude of low-density
lipoprotein cholesterol (LDL-C) lowering and rates of elevated liver enzymes …

Rosuvastatin is a new generation HMG-CoA reductase inhibitor which exhibits some unique
pharmacologic and pharmacokinetic properties. It has low extrahepatic tissue penetration …

Hypertriglyceridemia is associated with an increased risk of cardiovascular events and acute
pancreatitis. Along with lowering low-density lipoprotein cholesterol levels and raising high …

Fear of muscle toxicity remains a major reason that patients with hyperlipidemia are
undertreated. Recent evaluations of statin-induced rhabdomyolysis offer new insights on the …