Bioactive peptides are a group of biological molecules that are normally buried in the
structure of parent proteins and become active after the cleavage of the proteins. Another …

The recent outbreaks of infectious diseases caused by multidrug-resistant pathogens have
sounded a piercing alarm for the need of new effective antimicrobial agents to guard public …

The discovery of antibiotics marked a golden age in the revolution of human medicine.
However, decades later, bacterial infections remain a global healthcare threat, and a return …

The rapid increase in drug-resistant infections has presented a serious challenge to
antimicrobial therapies. The failure of the most potent antibiotics to kill “superbugs” …

Successful in vivo infection following pathogen entry requires the evasion and subversion of
multiple immunological barriers. Antimicrobial peptides (AMPs) are one of the first immune …

Burn injury is a severe form of trauma affecting more than 2 million people in North America
each year. Burn trauma is not a single pathophysiological event but a devastating injury that …

Cathelicidins are a group of antimicrobial peptides. Since their discovery, it has become
clear that they are an exceptional class of peptides, with some members having pleiotropic …

With the growing problem of the emergence of antibiotic-resistant bacteria, the search for
alternative ways to combat bacterial infections is extremely urgent. While analyzing the effect …

The oral mucosa is a primary barrier site and a portal for entry of microbes, food, and
airborne particles into the gastrointestinal tract. Nonetheless, mucosal immunity at this …

The pathogenesis of periodontitis involves the interplay of microbiota present in the
subgingival plaque and the host responses. Inflammation and destruction of periodontal …