Because of the high catalytic activities and substrate specificity, natural enzymes have been
widely used in industrial, medical, and biological fields, etc. Although promising, they often …

The liver is an organ that is particularly exposed to reactive oxygen species (ROS), which
not only arise during metabolic functions but also during the biotransformation of …

Chronic diseases represent a major challenge in world health. Metabolic syndrome is a
constellation of disturbances affecting several organs, and it has been proposed to be a liver …

Non-alcoholic fatty liver disease (NAFLD) is the hepatic manifestation of metabolic
syndrome. The underlying causes of the disease progression in NAFLD are unclear. Recent …

In recent years, the incidence of non-viral hepatocellular carcinoma (HCC) has increased
dramatically, which is probably related to the increased prevalence of metabolic syndrome …

Objectives Chronic-plus-binge ethanol feeding activates neutrophils and exacerbates liver
injury in mice. This study investigates how recent excessive drinking affects peripheral …

Chronic liver injury, resulted from different etiologies (eg, virus infection, alcohol abuse,
nonalcoholic steatohepatitis (NASH) and cholestasis) can lead to liver fibrosis characterized …

A peculiar role for oxidative stress in non-alcoholic fatty liver disease (NAFLD) and its
transition to the inflammatory complication non-alcoholic steatohepatitis (NASH), as well as …

Mammalian cells have evolved a unique strategy to protect themselves against oxidative
damage induced by reactive oxygen species (ROS). Especially, two transcription factors …

Nonalcoholic fatty liver disease (NAFLD) is characterized by hepatic fat accumulation in the
absence of excessive alcohol consumption and is strongly associated with obesity, type 2 …