The human immunodeficiency virus (HIV) genome encodes a total of three structural
proteins, two envelope proteins, three enzymes, and six accessory proteins. Studies over the …

The Gag proteins of HIV-1, like those of other retroviruses, are necessary and sufficient for
the assembly of virus-like particles. The roles played by HIV-1 Gag proteins during the life …

Publisher Summary This chapter focuses on recent biochemical and biophysical studies that
examine the nucleic acid chaperone function of HIV‐1 nucleocapsid protein (NC) and its …

Retrovirus particles contain a small, basic protein, the nucleocapsid (NC) protein, that
possessesnucleic acid chaperone'activity-that is, the NC protein can catalyze the …

RNA Packaging Page 1 RNA Packaging R. BERKOWITZ 1, J. FISHER2, and SP GOFF2
Introduction . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 177 2 Packaging …

The human immunodeficiency virus type 1 (HIV-1) nucleocapsid protein contains two copies
of a sequence motif, the cysteine-histidine box, that is conserved among retroviruses. To …

Both retroviruses and long terminal repeat (LTR) retrotransposons use cellular tRNAs as
primers for reverse transcription during their replication cycles. In retroviruses, primer tRNA …

The nucleocapsid (NC) protein of human immunodeficiency virus HIV‐1 (NCp7) is
responsible for packaging the viral RNA by recognizing a packaging site (PSI) on the viral …

Single molecule force spectroscopy is a powerful method that uses the mechanical
properties of DNA to explore DNA interactions. Here we describe how DNA stretching …

We have previously shown that a protein derived from the p7 nucleocapsid (NC) protein of
HIV type‐1 increases kcat/Km and kcat for cleavage of a cognate substrate by a …