Defining the metabolic requirements for the growth and colonization capacity of Campylobacter jejuni

D Hofreuter - Frontiers in cellular and infection microbiology, 2014 - frontiersin.org
During the last decade Campylobacter jejuni has been recognized as the leading cause of
bacterial gastroenteritis worldwide. This facultative intracellular pathogen is a member of the …

Recent advances in inhibitors of bacterial fatty acid synthesis type II (FASII) system enzymes as potential antibacterial agents

Y Wang, S Ma - ChemMedChem, 2013 - Wiley Online Library
Bacterial infections are a constant and serious threat to human health. With the increase of
multidrug resistance of clinically pathogenic bacteria, common antibiotic therapies have …

Structural and dynamical rationale for fatty acid unsaturation in Escherichia coli

GJ Dodge, A Patel, KL Jaremko… - Proceedings of the …, 2019 - National Acad Sciences
Fatty acid biosynthesis in α-and γ-proteobacteria requires two functionally distinct
dehydratases, FabA and FabZ. Here, mechanistic cross-linking facilitates the structural …

Transcriptome analysis reveals pathways responsible for the promoting effect of sucrose on astaxanthin accumulation in Haematococcus pluvialis under high light …

F Du, C Hu, X Sun, N Xu - Aquaculture, 2021 - Elsevier
Haematococcus pluvialis accumulates large amount of astaxanthin, a valuable
ketocarotenoid with super antioxidant activity, under stress conditions. Providing suitable …

Transcriptome analysis reveals the promoting effect of trisodium citrate on astaxanthin accumulation in Haematococcus pluvialis under high light condition

F Du, C Hu, X Sun, L Zhang, N Xu - Aquaculture, 2021 - Elsevier
Some organic carbons were able to further promote astaxanthin accumulation in
Haematococcus pluvialis under stress conditions. In this study, we demonstrate that adding …

The Actinobacillus pleuropneumoniae HMW1C-Like Glycosyltransferase Mediates N-Linked Glycosylation of the Haemophilus influenzae HMW1 Adhesin

KJ Choi, S Grass, S Paek, JW St. Geme III, HJ Yeo - PLoS One, 2010 - journals.plos.org
The Haemophilus influenzae HMW1 adhesin is an important virulence exoprotein that is
secreted via the two-partner secretion pathway and is glycosylated at multiple asparagine …

Active site comparisons and catalytic mechanisms of the hot dog superfamily

JW Labonte, CA Townsend - Chemical reviews, 2013 - ACS Publications
Active Site Comparisons and Catalytic Mechanisms of the Hot Dog Superfamily | Chemical
Reviews ACS ACS Publications C&EN CAS Find my institution Log In Chemical Reviews ACS …

Comparative proteomic analysis of seedling leaves of cold-tolerant and-sensitive spring soybean cultivars

X Tian, Y Liu, Z Huang, H Duan, J Tong, X He… - Molecular Biology …, 2015 - Springer
Cold stress adversely affects the growth and development of seedling of spring soybean.
Revealing responses in seedling to cold stress at proteomic level will help us to breed cold …

Molecular basis for the inhibition of β-hydroxyacyl-ACP dehydratase HadAB complex from Mycobacterium tuberculosis by flavonoid inhibitors

Y Dong, X Qiu, N Shaw, Y Xu, Y Sun, X Li, J Li… - Protein & …, 2015 - academic.oup.com
Dehydration is one of the key steps in the biosynthesis of mycolic acids and is vital to the
growth of Mycobacterium tuberculosis (Mtb). Consequently, stalling dehydration cures …

Structures of an unusual 3-hydroxyacyl dehydratase (FabZ) from a ladderane-producing organism with an unexpected substrate preference

A Dietl, K Wellach, P Mahadevan, N Mertes… - Journal of Biological …, 2023 - ASBMB
The genomes of anaerobic ammonium-oxidizing (anammox) bacteria contain a gene cluster
comprising genes of unusual fatty acid biosynthesis enzymes that were suggested to be …