Although yeast are unicellular and comparatively simple organisms, they have a sense of
time which is not related to reproduction cycles. The glycolytic pathway exhibits oscillatory …

Summary Short-period (40–50 min) synchronized metabolic oscillation was found in a
continuous culture of yeast Saccharomyces cerevisiae under aerobic conditions at low …

Continuous cultures of budding yeast are known to exhibit autonomous oscillations that
adversely affect bioreactor stability and productivity. We demonstrate that this phenomenon …

Metabolic overflow (enhanced uptake of substrate and secretion of intermediates) is a
phenomenon often observed for cells grown under substrate excess. Growth inhibition by …

The time structure of a biological system is at least as intricate as its spatial structure.
Whereas we have detailed information about the latter, our understanding of the former is …

The quasi‐steady‐states, marked by small fluctuations of residual glucose, ethanol, and
biomass concentrations, and sustainable oscillations marked by big fluctuations of these …

In the present work LC‐MS/MS was applied to measure the concentrations of intermediates
of glycolysis and TCA cycle during autonomous, cell‐cycle synchronized oscillations in …

When the yeast Saccharomyces cerevisiae was grown under aerobic continuous culture, an
autonomous shortperiod‐sustained oscillation appeared. This oscillation was observed in …

Background VHG fermentation is a promising process engineering strategy aiming at
improving ethanol titer, and thus saving energy consumption for ethanol distillation and …

In the present work dynamic changes of free intracellular amino acid pools during
autonomous oscillations of Saccharomyces cerevisiae were quantified in glucose‐limited …