This paper presents a comprehensive survey about the fundamental components of the
artificial pancreas (AP) system including insulin administration and delivery, glucose …

Blood glucose control algorithms have evolved since the beginnings of the artificial
pancreas in diabetes treatment. Although the main problem to solve remains as the …

We are witnessing the birth of a new variety of pharmacokinetics where non-integer-order
differential equations are employed to study the time course of drugs in the body: this is …

The scientific diagnosis and treatment of patients with diabetes require frequent blood
glucose testing and insulin delivery to normoglycemia. Therefore, an artificial pancreas with …

Motivation SBML is the most widespread language for the definition of biochemical models.
Although dozens of SBML simulators are available, there is a general lack of support to the …

Abstract A Cyber–Physical System (CPS) comprises physical as well as software
subsystems. Simulation-based approaches are typically used to support design and …

The regulation of blood glucose in Type-1 Diabetes Mellitus (T1DM) patient is being
extensively investigated by researchers. This research, therefore, has contributed to the …

In this article, a predictive controller using a type 3 fuzzy system is presented to regulate
blood glucose levels in type 1 diabetic patients. Using type 3 fuzzy systems leads to higher …

Hysteresis may be one of the most critical issues degrading the performance of the
automatic operation of robotic flexible ureteroscopy, ie, a robotic device handles the flexible …

Abstract Type 1 diabetes (T1D) mellitus is a systemic disease triggered by a local
autoimmune inflammatory reaction in insulin-producing cells that induce organ-wide, long …