Cytokine profile in relapsing-remitting multiple sclerosis patients and the association between progression and activity of the disease

AP Kallaur, SR Oliveira… - Molecular …, 2013 - spandidos-publications.com
Multiple sclerosis (MS) is a progressive immune-mediated disease caused by demyelination
of the central nervous system. Cytokines and their receptors have an important role in the …

The genetics of clinical outcome in multiple sclerosis

SV Ramagopalan, GC DeLuca, A Degenhardt… - Journal of …, 2008 - Elsevier
Multiple sclerosis (MS) is a common inflammatory disease of the central nervous system
(CNS), the clinical course of which varies considerably between patients. Genetic complexity …

Relationship between the IL‐4 gene promoter‐590C/T (rs2243250) polymorphism and susceptibility to autoimmune diseases: A meta‐analysis

LJ Qiu, J Ni, H Cen, PF Wen, M Zhang… - Journal of the …, 2015 - Wiley Online Library
Objective Studies investigating the association between interleukin (IL)‐4 gene promoter‐
590C/T (rs2243250) polymorphism and autoimmune diseases report conflicting results. To …

Genetic, immune-inflammatory, and oxidative stress biomarkers as predictors for disability and disease progression in multiple sclerosis

AP Kallaur, EMV Reiche, SR Oliveira, ANC Simão… - Molecular …, 2017 - Springer
The aim of this study was to evaluate the TNFβ Nco I polymorphism (rs909253) and immune-
inflammatory, oxidative, and nitrosative stress (IO&NS) biomarkers as predictors of disease …

Association of IL1A, IL1B, ILRN, IL6, IL10 and TNF-α polymorphisms with risk and clinical course of multiple sclerosis in a Polish population

D Mirowska-Guzel, G Gromadzka, A Mach… - Journal of …, 2011 - Elsevier
Single nucleotide polymorphisms in human pro-and anti-inflammatory genes, including
IL1RN VNTR (rs315952), IL1A 4845G> T (rs17561), L1B-511C> T (rs16944), IL6-174G> C …

Reduced expression of PD-1 in circulating CD4+ and CD8+ tregs is an early feature of RRMS

M Machcińska, M Kierasińska, M Michniowska… - International journal of …, 2022 - mdpi.com
Altered regulatory T cell (Treg) function could contribute to MS. The expression of activating
and inhibitory receptors influences the activity of Tregs. Our aim was to investigate T cell …

Association between tumor necrosis factor-alpha gene promoter polymorphism at position-308 and acne in Turkish patients

K Baz, M Emin Erdal, AC Yazıcı, F Söylemez… - Archives of …, 2008 - Springer
Acne is a multifactorial, chronic inflammatory disease of pilosebaceous unit in which
cytokines have been implicated in the pathogenesis. Although it is thought to be an inherited …

Necrostatin‑1 ameliorates the pathogenesis of experimental autoimmune encephalomyelitis by suppressing apoptosis and necroptosis of oligodendrocyte precursor …

Y Wang, L Guo, J Wang, W Shi… - Experimental and …, 2019 - spandidos-publications.com
Multiple sclerosis (MS) is an autoimmune disease of the central nervous system
characterized by neuronal demyelination. MS pathogenesis occurs via multiple …

CTLA4 exon 1 and promoter polymorphisms in patients with multiple sclerosis

G Yousefipour, N Erfani, M Momtahan… - Acta neurologica …, 2009 - Wiley Online Library
Objective–The polymorphisms of exon 1 (+ 49 A/G) and promoter regions (− 1722 T/C,−
1661 A/G and− 318 C/T) of cytotoxic T lymphocyte antigen 4 (CTLA4) and also haplotypes …

Anthropometric indices, nutrient intakes and health-related characteristics of patients with multiple sclerosis: a cross-sectional study

M Moazen, Z Mousavi-Shirazi-Fard… - Nutritional …, 2024 - Taylor & Francis
Background Multiple sclerosis (MS) is accompanied by many health-related issues. This
study aimed to evaluate the anthropometric indices, nutrient intakes and health-related …