Assessment of right ventricular function in the research setting: knowledge gaps and pathways forward. An Official American Thoracic Society Research Statement
Background: Right ventricular (RV) adaptation to acute and chronic pulmonary hypertensive
syndromes is a significant determinant of short-and long-term outcomes. Although …
syndromes is a significant determinant of short-and long-term outcomes. Although …
The latest in animal models of pulmonary hypertension and right ventricular failure
Pulmonary hypertension (PH) describes heterogeneous population of patients with a mean
pulmonary arterial pressure> 20 mm Hg. Rarely, PH presents as a primary disorder but is …
pulmonary arterial pressure> 20 mm Hg. Rarely, PH presents as a primary disorder but is …
Markers of myocardial damage predict mortality in patients with aortic stenosis
S Kwak, RJ Everett, TA Treibel, S Yang… - Journal of the American …, 2021 - jacc.org
Background Cardiovascular magnetic resonance (CMR) is increasingly used for risk
stratification in aortic stenosis (AS). However, the relative prognostic power of CMR markers …
stratification in aortic stenosis (AS). However, the relative prognostic power of CMR markers …
Molecular mechanisms of pulmonary vascular remodeling in pulmonary arterial hypertension
JA Leopold, BA Maron - International journal of molecular sciences, 2016 - mdpi.com
Pulmonary arterial hypertension (PAH) is a devastating disease that is precipitated by
hypertrophic pulmonary vascular remodeling of distal arterioles to increase pulmonary artery …
hypertrophic pulmonary vascular remodeling of distal arterioles to increase pulmonary artery …
Emerging concepts in the molecular basis of pulmonary arterial hypertension: part II: neurohormonal signaling contributes to the pulmonary vascular and right …
BA Maron, JA Leopold - Circulation, 2015 - Am Heart Assoc
Pulmonary arterial hypertension (PAH) is defined foremost by a distinct pulmonary vascular
pathophenotype that occurs as a result of dysregulated vascular cell proliferation, intimal …
pathophenotype that occurs as a result of dysregulated vascular cell proliferation, intimal …
New directions in right ventricular assessment using 3-dimensional echocardiography
Importance Before the introduction of 3-dimensional echocardiography, estimations of right
ventricular (RV) size and function by echocardiography were limited to regional …
ventricular (RV) size and function by echocardiography were limited to regional …
The use of multimodality cardiovascular imaging to assess right ventricular size and function
Right ventricular (RV) size and function have been found to be important predictors of
cardiovascular morbidity and mortality in patients with various conditions. However, non …
cardiovascular morbidity and mortality in patients with various conditions. However, non …
Frailty trajectories in adult lung transplantation: a cohort study
A Venado, C McCulloch, JR Greenland, P Katz… - The Journal of Heart and …, 2019 - Elsevier
BACKGROUND Frailty is common in adults with advanced lung disease and is associated
with death before and after lung transplantation. We aimed to determine whether frailty …
with death before and after lung transplantation. We aimed to determine whether frailty …
Elucidating the clinical implications and pathophysiology of pulmonary hypertension in heart failure with preserved ejection fraction: a call to action: a science advisory …
EL Brittain, T Thenappan, JH Huston, V Agrawal… - Circulation, 2022 - Am Heart Assoc
This science advisory focuses on the need to better understand the epidemiology,
pathophysiology, and treatment of pulmonary hypertension in patients with heart failure with …
pathophysiology, and treatment of pulmonary hypertension in patients with heart failure with …
Intratracheal gene delivery of SERCA2a ameliorates chronic post-capillary pulmonary hypertension: a large animal model
Background: Pulmonary hypertension (PH) is characterized by pulmonary arterial
remodeling that results in increased pulmonary vascular resistance, right ventricular (RV) …
remodeling that results in increased pulmonary vascular resistance, right ventricular (RV) …