Recent advances in machine learning applications in metabolic engineering

P Patra, BR Disha, P Kundu, M Das, A Ghosh - Biotechnology Advances, 2023 - Elsevier
Metabolic engineering encompasses several widely-used strategies, which currently hold a
high seat in the field of biotechnology when its potential is manifesting through a plethora of …

Systems metabolic engineering meets machine learning: a new era for data‐driven metabolic engineering

KV Presnell, HS Alper - Biotechnology journal, 2019 - Wiley Online Library
The recent increase in high‐throughput capacity of 'omics datasets combined with advances
and interest in machine learning (ML) have created great opportunities for systems …

[HTML][HTML] Digitally enabled approaches for the scale up of mammalian cell bioreactors

MK Alavijeh, I Baker, YY Lee, SL Gras - Digital Chemical Engineering, 2022 - Elsevier
With recent advances in digitisation and big data analytics, more pharmaceutical firms are
adopting digital tools to achieve modernisation. The biological phenomena within …

Learning with multiple pairwise kernels for drug bioactivity prediction

A Cichonska, T Pahikkala, S Szedmak… - …, 2018 - academic.oup.com
Motivation Many inference problems in bioinformatics, including drug bioactivity prediction,
can be formulated as pairwise learning problems, in which one is interested in making …

Leveraging knowledge engineering and machine learning for microbial bio-manufacturing

T Oyetunde, FS Bao, JW Chen, HG Martin… - Biotechnology …, 2018 - Elsevier
Genome scale modeling (GSM) predicts the performance of microbial workhorses and helps
identify beneficial gene targets. GSM integrated with intracellular flux dynamics, omics, and …

Distribution Model of Personal Protective Equipment (PPE) Using the Spatial Dominance Test and Decision Tree Algorithm

V Purwayoga, S Yuliyanti, A Nurkholis… - … : International Journal on …, 2024 - joiv.org
The COVID-19 case has developed positively, but preventive measures must be taken to
anticipate SARS-CoV-2 mutations. Anticipation can include policies, preparing health …

Promoter element engineering towards modulated and consistent gene expression

KV Presnell - 2023 - repositories.lib.utexas.edu
Metabolic engineering requires precise control over expression strength, which can be
effectively accomplished through engineering of the promoter element. In this regard, there …

[PDF][PDF] Digital Chemical Engineering

MK Alavijeh, I Baker, YY Lee, SL Gras - minerva-access.unimelb.edu.au
abstract With recent advances in digitisation and big data analytics, more pharmaceutical
firms are adopting digital tools to achieve modernisation. The biological phenomena within …

Interactive Higher-Order Network Analysis

R Rossi, N Ahmed, E Koh - 2018 IEEE International …, 2018 - ieeexplore.ieee.org
Higher-order network modeling and analysis is vital to understand the structures governing
the configuration and behavior of complex networks. While network motifs are known to be …

Recent Advances in Molecular Approaches for Mining Potential Candidate Genes of Trichoderma for Biofuel

R Salwan, A Sharma, V Sharma - Fungal Biotechnology and …, 2020 - Springer
Trichoderma, a filamentous ascomycete, belonging to order Hypocreales, is well-known for
its ability to secrete a number of glycosyl hydrolases and other enzymes. The ability of …