Molecular genetics and emerging therapies for retinitis pigmentosa: Basic research and clinical perspectives

MF Dias, K Joo, JA Kemp, SL Fialho… - Progress in retinal and …, 2018 - Elsevier
Retinitis Pigmentosa (RP) is a hereditary retinopathy that affects about 2.5 million people
worldwide. It is characterized with progressive loss of rods and cones and causes severe …

[HTML][HTML] Biomaterials to enhance stem cell transplantation

BN Kharbikar, P Mohindra, TA Desai - Cell Stem Cell, 2022 - cell.com
The successful transplantation of stem cells has the potential to transform regenerative
medicine approaches and open promising avenues to repair, replace, and regenerate …

Bone marrow-derived mesenchymal stem cells-derived exosomes promote survival of retinal ganglion cells through miRNA-dependent mechanisms

B Mead, S Tomarev - Stem cells translational medicine, 2017 - academic.oup.com
The loss of retinal ganglion cells (RGC) and their axons is one of the leading causes of
blindness and includes traumatic (optic neuropathy) and degenerative (glaucoma) eye …

Clinical potential and current progress of dental pulp stem cells for various systemic diseases in regenerative medicine: a concise review

Y Yamada, S Nakamura-Yamada, K Kusano… - International journal of …, 2019 - mdpi.com
Dental pulp stem cells (DPSCs) are mesenchymal stem cells (MSCs) that have multipotent
differentiation and a self-renewal ability. They have been useful not only for dental diseases …

[HTML][HTML] Bioenergetic crosstalk between mesenchymal stem cells and various ocular cells through the intercellular trafficking of mitochondria

D Jiang, FX Chen, H Zhou, YY Lu, H Tan, SJ Yu… - Theranostics, 2020 - ncbi.nlm.nih.gov
Rationale: Mitochondrial disorders preferentially affect tissues with high energy
requirements, such as the retina and corneal endothelium, in human eyes. Mesenchymal …

Iron oxide nanoparticles in regenerative medicine and tissue engineering

RP Friedrich, I Cicha, C Alexiou - Nanomaterials, 2021 - mdpi.com
In recent years, many promising nanotechnological approaches to biomedical research
have been developed in order to increase implementation of regenerative medicine and …

Stem cells applications in regenerative medicine and disease therapeutics

RS Mahla - International journal of cell biology, 2016 - Wiley Online Library
Regenerative medicine, the most recent and emerging branch of medical science, deals
with functional restoration of tissues or organs for the patient suffering from severe injuries or …

Transplanted human cones incorporate into the retina and function in a murine cone degeneration model

SJ Gasparini, K Tessmer, M Reh… - The Journal of …, 2022 - Am Soc Clin Investig
Once human photoreceptors die, they do not regenerate, thus, photoreceptor transplantation
has emerged as a potential treatment approach for blinding diseases. Improvements in …

Retinitis pigmentosa: progress in molecular pathology and biotherapeutical strategies

W Liu, S Liu, P Li, K Yao - International Journal of Molecular Sciences, 2022 - mdpi.com
Retinitis pigmentosa (RP) is genetically heterogeneous retinopathy caused by
photoreceptor cell death and retinal pigment epithelial atrophy that eventually results in …

Neuroprotection, growth factors and BDNF-TrkB signalling in retinal degeneration

A Kimura, K Namekata, X Guo, C Harada… - International journal of …, 2016 - mdpi.com
Neurotrophic factors play key roles in the development and survival of neurons. The potent
neuroprotective effects of neurotrophic factors, including brain-derived neurotrophic factor …