Tetraspanins are a large, highly conserved family of four-pass transmembrane (TM) proteins
that play critical roles in a variety of essential cellular functions, including cell migration …

Hepatitis C virus (HCV) entry is among the best-studied uptake processes for human
pathogenic viruses. Uptake follows a spatially and temporally tightly controlled program …

Summary Interleukin-35 (IL-35) is an immunosuppressive cytokine composed of Epstein-
Barr-virus-induced protein 3 (Ebi3) and IL-12α chain (p35) subunits, yet the forms that IL-35 …

Hepatitis C virus (HCV) infection is a causal agent of chronic liver disease, cirrhosis and
hepatocellular carcinoma in humans, and afflicts more than 70 million people worldwide …

Hepatitis C virus (HCV) uses a hybrid entry mechanism. Current structural data suggest that
upon exposure to low pH and Cluster of Differentiation 81 (CD81), the amino terminus of …

Continually repeating outbreaks of pathogenic viruses necessitate the construction of
effective antiviral strategies. Therefore, the development of new specific antiviral drugs in a …

Inter-cellular and inter-kingdom signaling systems of various levels of complexity regulate
pathogenic and mutualistic interactions between bacteria, parasites, and fungi and animal …

Tetraspanins (TETs) function as key molecular scaffolds for surface signal recognition and
transduction via the assembly of tetraspanin-enriched microdomains. TETs' function in …

The research of extracellular vesicles (EVs) has boomed in the last decade, with the promise
of them functioning as target‐directed drug delivery vehicles, able to modulate proliferation …

This paper is aimed at the development of a biosensor for direct detection of Hepatitis C
virus (HCV) surface antigen: envelope protein (E2). A recombinant LEL fragment of …