[HTML][HTML] Biochemical markers of musculoskeletal health and aging to be assessed in clinical trials of drugs aiming at the treatment of sarcopenia: consensus paper …

A Ladang, C Beaudart, JY Reginster… - Calcified Tissue …, 2023 - Springer
In clinical trials, biochemical markers provide useful information on the drug's mode of
action, therapeutic response and side effect monitoring and can act as surrogate endpoints …

C‐terminal agrin fragment as a biomarker of muscle wasting and weakness: a narrative review

E Monti, F Sarto, R Sartori, G Zanchettin… - Journal of Cachexia …, 2023 - Wiley Online Library
Ageing is accompanied by an inexorable loss of muscle mass and functionality and
represents a major risk factor for numerous diseases such as cancer, diabetes and …

A multistrain probiotic improves handgrip strength and functional capacity in patients with COPD: A randomized controlled trial

A Karim, T Muhammad, MS Iqbal, R Qaisar - Archives of gerontology and …, 2022 - Elsevier
Purpose The age-related muscle loss, termed sarcopenia and functional dependency, are
common findings in patients with chronic obstructive pulmonary disease (COPD). However …

[HTML][HTML] South asian working action group on SARCOpenia (SWAG-SARCO)–A consensus document

M Dhar, N Kapoor, K Suastika, ME Khamseh… - Osteoporosis and …, 2022 - Elsevier
Abstract The South Asian population is rapidly ageing and sarcopenia is likely to become a
huge burden in this region if proper action is not taken in time. Several sarcopenia …

Elevated plasma zonulin and CAF22 are correlated with sarcopenia and functional dependency at various stages of Alzheimer's diseases

A Karim, MS Iqbal, T Muhammad, F Ahmad… - Neuroscience …, 2022 - Elsevier
Age-related muscle decline, termed sarcopenia, is closely linked to dementia; however, its
causative factors in patients with Alzheimer's disease (AD) are poorly characterized. We …

Plasma zonulin correlates with cardiac dysfunction and poor physical performance in patients with chronic heart failure

F Ahmad, A Karim, J Khan, R Qaisar - Life Sciences, 2022 - Elsevier
Aims An aberrant intestinal permeability is often associated with systemic inflammation and
cardiovascular diseases accompanied by compromised physical performance. However, the …

Effects of a 2‐year exercise training on neuromuscular system health in older individuals with low muscle function

E Monti, S Tagliaferri, S Zampieri… - Journal of cachexia …, 2023 - Wiley Online Library
Background Ageing is accompanied by a progressive loss of skeletal muscle mass and
strength, potentially determining the insurgence of sarcopenia. Evidence suggests that …

[HTML][HTML] Sarcopenia and frailty in heart failure: is there a biomarker signature?

R Sato, M Vatic, GWP da Fonseca… - Current heart failure …, 2022 - Springer
Abstract Purpose of Review Sarcopenia and frailty are common in patients with heart failure
(HF) and are strongly associated with prognosis. This review aims to examine promising …

Targeting neuromuscular junction to treat neuromuscular disorders

R Qaisar - Life Sciences, 2023 - Elsevier
The integrity and preservation of the neuromuscular junction (NMJ), the interface between
the motor neuron and skeletal muscle, is critical for maintaining a healthy skeletal muscle …

[HTML][HTML] Elevated plasma CAF22 are incompletely restored six months after COVID-19 infection in older men

A Karim, T Muhammad, MS Iqbal, R Qaisar - Experimental Gerontology, 2023 - Elsevier
Introduction The long-term complications of COVID-19 appear as significant health
problems. However, the long-term muscle decline in these patients is poorly characterized …