The basic properties of gold nanoparticles and their applications in tumor diagnosis and treatment

X Bai, Y Wang, Z Song, Y Feng, Y Chen… - International journal of …, 2020 - mdpi.com
Gold nanoparticles (AuNPs) have been widely studied and applied in the field of tumor
diagnosis and treatment because of their special fundamental properties. In order to make …

Gold nanoparticles for applications in cancer radiotherapy: Mechanisms and recent advancements

S Her, DA Jaffray, C Allen - Advanced drug delivery reviews, 2017 - Elsevier
Gold nanoparticles (AuNPs) have emerged as novel radiosensitizers owing to their high X-
ray absorption, synthetic versatility, and unique chemical, electronic and optical properties …

[HTML][HTML] Nanoparticles for radiation therapy enhancement: the key parameters

P Retif, S Pinel, M Toussaint, C Frochot, R Chouikrat… - Theranostics, 2015 - ncbi.nlm.nih.gov
This review focuses on the radiosensitization strategies that use high-Z nanoparticles. It
does not establish an exhaustive list of the works in this field but rather propose constructive …

Nanoparticle radio-enhancement: principles, progress and application to cancer treatment

Z Kuncic, S Lacombe - Physics in Medicine & Biology, 2018 - iopscience.iop.org
Enhancement of radiation effects by high-atomic number nanoparticles (NPs) has been
increasingly studied for its potential to improve radiotherapeutic efficacy. The underlying …

Roadmap for metal nanoparticles in radiation therapy: Current status, translational challenges, and future directions

J Schuemann, AF Bagley, R Berbeco… - Physics in Medicine …, 2020 - iopscience.iop.org
This roadmap outlines the potential roles of metallic nanoparticles (MNPs) in the field of
radiation therapy. MNPs made up of a wide range of materials (from Titanium, Z= 22, to …

Progress in research on gold nanoparticles in cancer management

J Peng, X Liang - Medicine, 2019 - journals.lww.com
Conclusion: AuNPs have many properties that are of great value for the diagnosis and
treatment of tumors. AuNPs are small in size and can penetrate widely and deposit on the …

Engineering gold-based radiosensitizers for cancer radiotherapy

N Goswami, Z Luo, X Yuan, DT Leong, J Xie - Materials Horizons, 2017 - pubs.rsc.org
Radiotherapy remains a major modality in cancer therapy. The main goal of radiotherapy is
to shrink tumors and kill cancer cells by using high-energy radiation, such as X-rays and γ …

Roadmap to clinical use of gold nanoparticles for radiation sensitization

J Schuemann, R Berbeco, DB Chithrani, SH Cho… - International Journal of …, 2016 - Elsevier
The past decade has seen a dramatic increase in interest in the use of gold nanoparticles
(GNPs) as radiation sensitizers for radiation therapy. This interest was initially driven by their …

Breaking the depth dependence by nanotechnology‐enhanced X‐ray‐excited deep cancer theranostics

W Fan, W Tang, J Lau, Z Shen, J Xie, J Shi… - Advanced …, 2019 - Wiley Online Library
The advancements in nanotechnology have created multifunctional nanomaterials aimed at
enhancing diagnostic accuracy and treatment efficacy for cancer. However, the ability to …

Selective targeting of brain tumors with gold nanoparticle-induced radiosensitization

DY Joh, L Sun, M Stangl, A Al Zaki, S Murty… - PloS one, 2013 - journals.plos.org
Successful treatment of brain tumors such as glioblastoma multiforme (GBM) is limited in
large part by the cumulative dose of Radiation Therapy (RT) that can be safely given and the …