Deep brain stimulation in movement disorders: from experimental surgery to evidence‐based therapy

P Krack, J Volkmann, G Tinkhauser… - Movement …, 2019 - Wiley Online Library
Deep brain stimulation (DBS) of 3 different targets is the most important therapeutic
innovation of the past 30 years for patients with fluctuating Parkinson's disease (PD) …

History, applications, and mechanisms of deep brain stimulation

S Miocinovic, S Somayajula, S Chitnis… - JAMA neurology, 2013 - jamanetwork.com
Deep brain stimulation (DBS) is an effective surgical treatment for medication-refractory
hypokinetic and hyperkinetic movement disorders, and it is being explored for a variety of …

Clinical presentation and management of dyskinetic cerebral palsy

E Monbaliu, K Himmelmann, JP Lin, E Ortibus… - The Lancet …, 2017 - thelancet.com
Cerebral palsy is the most frequent cause of severe physical disability in childhood.
Dyskinetic cerebral palsy (DCP) is the second most common type of cerebral palsy after …

Emerging concepts in the physiological basis of dystonia

A Quartarone, M Hallett - Movement Disorders, 2013 - Wiley Online Library
Work over the past 2 decades has led to substantial changes in our understanding of
dystonia pathophysiology. Three general abnormalities appear to underlie the …

Treatment of motor and non-motor features of Parkinson's disease with deep brain stimulation

A Fasano, A Daniele, A Albanese - The Lancet Neurology, 2012 - thelancet.com
Deep brain stimulation (DBS) is an established procedure for the symptomatic treatment of
Parkinson's disease. Several deep brain nuclei have been stimulated, producing a wide …

Bilateral deep-brain stimulation of the globus pallidus in primary generalized dystonia

M Vidailhet, L Vercueil, JL Houeto… - … England Journal of …, 2005 - Mass Medical Soc
Background Severe forms of dystonia respond poorly to medical treatment. Deep-brain
stimulation is a reversible neurosurgical procedure that has been used for the treatment of …

Pallidal deep-brain stimulation in primary generalized or segmental dystonia

A Kupsch, R Benecke, J Müller… - … England Journal of …, 2006 - Mass Medical Soc
Background Neurostimulation of the internal globus pallidus has been shown to be effective
in reducing symptoms of primary dystonia. We compared this surgical treatment with sham …

EFNS guidelines on diagnosis and treatment of primary dystonias

A Albanese, F Asmus, KP Bhatia… - European Journal of …, 2011 - Wiley Online Library
Objectives: To provide a revised version of earlier guidelines published in 2006.
Background: Primary dystonias are chronic and often disabling conditions with a …

Uncovering the mechanism (s) of action of deep brain stimulation: activation, inhibition, or both

CC McIntyre, M Savasta, L Kerkerian-Le Goff… - Clinical …, 2004 - Elsevier
High-frequency deep brain stimulation (DBS) of the thalamus or basal ganglia represents an
effective clinical technique for the treatment of several medically refractory movement …

Introduction to the programming of deep brain stimulators

J Volkmann, J Herzog, F Kopper… - … : official journal of the …, 2002 - Wiley Online Library
The clinical success of deep brain stimulation (DBS) for treating Parkinson's disease, tremor,
or dystonia critically depends on the quality of postoperative neurologic management …