Peptides exhibit lower affinity and a shorter half-life in the body than antibodies. Conversely,
peptides demonstrate higher efficiency in tissue penetration and cell internalization than …

Breast cancer is one of the leading causes of cancer-related morbidity and mortality in
women worldwide. Early diagnosis and effective treatment of all types of cancers are crucial …

Breast cancer (BC) is one of the most widely diagnosed cancers and a leading cause of
cancer death among women worldwide. Globally, BC is the second most frequent cancer …

Reproductive hormones play a crucial role in the growth and maintenance of the
mammalian skeleton. Indeed, the biological significance for this hormonal regulation of …

Sex steroids are major promoters of the growth of breast and prostate cancers. This Review
by Poutanen et al. describes the development of treatments for these cancer types that act to …

The journey of chemotherapeutic drugs from the site of administration to the site of action is
confronted by several factors including low bioavailability, uneven distribution in major …

For many years, luteinizing hormone-releasing hormone or gonadotropin-releasing
hormone (GnRH) analogs have been used to treat androgen or estrogen-dependent tumors …

In this review, we analyzed existing literature regarding the use of Gonadotropin-releasing
Hormone (GnRH) analogues (agonists, antagonists) as a co-treatment to chemotherapy and …

Human sexual and reproductive development is regulated by the hypothalamic-pituitary-
gonadal (HPG) axis, which is primarily controlled by the gonadotropin-releasing hormone …

Chemotherapy and endocrine therapies are mainstays of treatment for early and advanced
hormone receptor-positive (HR+) breast cancer. In premenopausal women with HR+ tumors …