Abstract Neurofibromatosis type 1 (NF1) is a common genetic disorder that predisposes
affected individuals to tumours. The NF1 gene encodes a RAS GTPase-activating protein …

ABSTRACT A vast array of oncogenic variants has been identified for anaplastic lymphoma
kinase (ALK). Therefore, there is a need to better understand the role of ALK in cancer …

The burgeoning field of anaplastic lymphoma kinase (ALK) in cancer encompasses many
cancer types, from very rare cancers to the more prevalent non-small-cell lung cancer …

Malignant peripheral nerve sheath tumors (MPNSTs) are aggressive, invasive cancer that
comprise around 10% of all soft tissue sarcomas and develop in about 8–13% of patients …

Mushroom body (MB)-dependent olfactory learning in Drosophila provides a powerful model
to investigate memory mechanisms. MBs integrate olfactory conditioned stimulus (CS) inputs …

Abstract Neurofibromatosis type 1 (NF1) is an autosomal dominant genetic disease and one
of the most common inherited tumor predisposition syndromes, affecting 1 in 3000 …

ABSTRACT Introduction: Neurofibromatosis type 1 (NF1) is an autosomal dominantly
inherited tumor predisposition syndrome with an incidence of one in 3000–4000 individuals …

Anaplastic lymphoma kinase (ALK) is a validated molecular target in several ALK-
rearranged malignancies, particularly in non-small-cell lung cancer (NSCLC), which has …

Neurodevelopmental disorders (NDDs) include a large number of conditions such as Fragile
X syndrome, autism spectrum disorders and Down syndrome, among others. They are …

Neurofibromin controls many cell processes, such as growth, learning, and memory. If
neurofibromin is not working properly, it can lead to health problems, including issues with …