New insights into adipokines in gestational diabetes mellitus

J Valencia-Ortega, R González-Reynoso… - International Journal of …, 2022 - mdpi.com
Gestational diabetes mellitus (GDM) is the most common metabolic disorder of pregnancy
and has considerable short-and long-term consequences for the health of both the mother …

Fetomaternal expression of glucose transporters (GLUTs)—biochemical, cellular and clinical aspects

R Sibiak, K Ozegowska, E Wender-Ozegowska… - Nutrients, 2022 - mdpi.com
Several types of specialized glucose transporters (GLUTs) provide constant glucose
transport from the maternal circulation to the developing fetus through the placental barrier …

Shared developmental pathways of the placenta and fetal heart

A Mahadevan, A Tipler, H Jones - Placenta, 2023 - Elsevier
Congenital heart defects (CHD) remain the most common class of birth defect worldwide,
affecting 1 in every 110 live births. A host of clinical and morphological indicators of …

The physiological basis with uterine myometrium contractions from electro-mechanical/hormonal myofibril function to the term and preterm labor

FZ Zangeneh, S Hantoushzadeh - Heliyon, 2023 - cell.com
Background Most labor-related problems can be attributed to the uterine myometrium
muscle, as this irritable tissue must suppress its irritability potential during pregnancy …

Placental nutrient transporters and maternal fatty acids in SGA, AGA, and LGA newborns from mothers with and without obesity

JA Garcia-Santillan… - Frontiers in Cell and …, 2022 - frontiersin.org
Adverse environmental factors in early life result in fetal metabolic programming and
increased risk of adult diseases. Birth weight is an indirect marker of the intrauterine …

First comparative evaluation of short-chain fatty acids and vitamin-K-dependent proteins levels in mother–newborn pairs at birth

T Ilyés, M Pop, M Surcel, DM Pop, R Rusu, CN Silaghi… - Life, 2023 - mdpi.com
Background: The interplay between vitamin K (vitK)(as carboxylation cofactor, partially
produced by the gut microbiota) and short-chain fatty acids (SCFAs), the end-product of fiber …

Placental Drug Delivery to Treat Pre‐Eclampsia and Fetal Growth Restriction

V Deepak, L El‐Balawi, LK Harris - Small, 2024 - Wiley Online Library
Pre‐eclampsia and fetal growth restriction (FGR) continue to cause unacceptably high levels
of morbidity and mortality, despite significant pharmaceutical and technological advances in …

Bridging the gap: glucose transporters, Alzheimer's, and future therapeutic prospects

M Albaik, D Sheikh Saleh, D Kauther… - Frontiers in Cell and …, 2024 - frontiersin.org
Glucose is the major source of chemical energy for cell functions in living organisms. The
aim of this mini-review is to provide a clearer and simpler picture of the fundamentals of …

Protein O-GlcNAcylation as a nutrient sensor signaling placental dysfunction in hypertensive pregnancy

RR dos Passos Junior, RA de Freitas… - Frontiers in …, 2022 - frontiersin.org
Introduction During pregnancy, arterial hypertension may impair placental function, which is
critical for a healthy baby's growth. Important proteins during placentation are known to be …

The glucose transporter GLUT12, a new actor in obesity and cancer

M Burgos, E Gil-Iturbe, A Idoate-Bayón… - Journal of Physiology …, 2024 - Springer
Obesity constitutes a global health epidemic which worsens the main leading death causes
such as type 2 diabetes, cardiovascular diseases, and cancer. Changes in the metabolism …