Polymeric hydrogels are fascinating platforms as 3D scaffolds for tissue repair and delivery
systems of therapeutic molecules and cells. Among others, methacrylated gelatin (GelMA) …

Gene therapy is the administration of foreign genomic material into the host tissue to modify
the expression of a gene product or to change the biological properties of cells for …

Damage to cartilage tissues is often difficult to repair owing to chronic inflammation and a
lack of bioactive factors. Therefore, developing bioactive materials, such as hydrogels acting …

Extracellular vesicles (EVs), as natural carriers of bioactive cargo, have a unique
micro/nanostructure, bioactive composition, and characteristic morphology, as well as …

Cartilage regeneration remains a current challenge with no satisfactory strategy in surgery.
Hydrogels with structurally and biochemically biomimicking characteristics have been …

Articular cartilage injury is a frequent worldwide disease, while effective treatment is urgently
needed. Due to lack of blood vessels and nerves, the ability of cartilage to self-repair is …

Tissue regeneration technology has been rapidly developed and widely applied in tissue
engineering and repair. Compared with traditional approaches like surgical treatment, the …

Tissue engineering (TE) is a rapidly growing interdisciplinary field, which aims to restore or
improve lost tissue function. Despite that TE was introduced more than 20 years ago …

Tumor nanovaccines have potential applications in the prevention and treatment of
malignant tumors. However, it remains a longstanding challenge in exploiting efficient …

Extracellular matrix (ECM) metabolism balance is essential for maintaining tissue structure
and function. However, the complex crosstalk between the ECM, resident cellular, and tissue …