Small bioactive peptides for biomaterials design and therapeutics

IW Hamley - Chemical reviews, 2017 - ACS Publications
This review is aimed to provide a concise yet extensive survey of key short bioactive peptide
sequences for a range of applications ranging from biomaterials development to peptides …

Orally active peptides: is there a magic bullet?

AFB Räder, M Weinmüller, F Reichart… - Angewandte Chemie …, 2018 - Wiley Online Library
For decades, the development of peptides as potential drugs was aimed solely at peptides
with the highest affinity, receptor selectivity, or stability against enzymatic degradation …

Glycosylation, an effective synthetic strategy to improve the bioavailability of therapeutic peptides

SV Moradi, WM Hussein, P Varamini, P Simerska… - Chemical …, 2016 - pubs.rsc.org
Glycosylation of peptides is a promising strategy for modulating the physicochemical
properties of peptide drugs and for improving their absorption through biological …

Recent developments in antimicrobial-peptide-conjugated gold nanoparticles

U Rajchakit, V Sarojini - Bioconjugate chemistry, 2017 - ACS Publications
The escalation of multidrug-resistant pathogens has created a dire need to develop novel
ways of addressing this global therapeutic challenge. Because of their antimicrobial …

Chemical methods for peptide and protein production

S Chandrudu, P Simerska, I Toth - Molecules, 2013 - mdpi.com
Since the invention of solid phase synthetic methods by Merrifield in 1963, the number of
research groups focusing on peptide synthesis has grown exponentially. However, the …

Applications of thiol-ene chemistry for peptide science

MD Nolan, EM Scanlan - Frontiers in chemistry, 2020 - frontiersin.org
Radical thiol-ene chemistry has been demonstrated for a range of applications in peptide
science, including macrocyclization, glycosylation and lipidation amongst a myriad of others …

[HTML][HTML] Facile and efficient encapsulation of antimicrobial peptides via crosslinked DNA nanostructures and their application in wound therapy

S Obuobi, HKL Tay, NDT Tram, V Selvarajan… - Journal of Controlled …, 2019 - Elsevier
There is growing interest in the development of nucleic acid nanostructures as smart
functional materials for applications in drug delivery. Inspired by the diverse physical …

Recent advances in the development of peptide vaccines and their delivery systems against group a streptococcus

A Azuar, W Jin, S Mukaida, WM Hussein, I Toth… - Vaccines, 2019 - mdpi.com
Group A Streptococcus (GAS) infection can cause a variety of diseases in humans, ranging
from common sore throats and skin infections, to more invasive diseases and life …

Peptide-based subunit nanovaccines

M Skwarczynski, I Toth - Current drug delivery, 2011 - ingentaconnect.com
Classical vaccines incorporating live or attenuated microorganisms possess several
disadvantages and cannot be applied against cancer and some pathogens. Modern …

Oromucosal delivery of macromolecules: Challenges and recent developments to improve bioavailability

M Rawas-Qalaji, HE Thu, Z Hussain - Journal of Controlled Release, 2022 - Elsevier
Owing to their biological diversity, high potency, good tolerability, low immunogenicity, site-
specific activity, and great efficacy, macromolecular drugs (ie, proteins and peptides …