[HTML][HTML] The impact of Di-(2-ethylhexyl) Phthalate and Mono (2-ethylhexyl) Phthalate in placental development, function, and pathophysiology

LD Martínez-Razo, A Martínez-Ibarra… - Environment …, 2021 - Elsevier
Abstract Di (2-ethylhexyl) phthalate (DEHP) is a chemical widely distributed in the
environment as is extensively used in the plastic industry. DEHP is considered an endocrine …

Heightened susceptibility: A review of how pregnancy and chemical exposures influence maternal health

J Varshavsky, A Smith, A Wang, E Hom, M Izano… - Reproductive …, 2020 - Elsevier
Pregnancy is a unique period when biological changes can increase sensitivity to chemical
exposures. Pregnant women are exposed to multiple environmental chemicals via air, food …

Placental Mitochondrial DNA Content and Particulate Air Pollution during in Utero Life

BG Janssen, E Munters, N Pieters… - Environmental …, 2012 - ehp.niehs.nih.gov
Background: Studies emphasize the importance of particulate matter (PM) in the formation of
reactive oxygen species and inflammation. We hypothesized that these processes can …

Placental DNA hypomethylation in association with particulate air pollution in early life

BG Janssen, L Godderis, N Pieters, K Poels… - Particle and fibre …, 2013 - Springer
Background There is evidence that altered DNA methylation is an important epigenetic
mechanism in prenatal programming and that developmental periods are sensitive to …

Urinary paraben concentrations among pregnant women and their matching newborn infants of Korea, and the association with oxidative stress biomarkers

S Kang, S Kim, J Park, HJ Kim, J Lee, G Choi… - Science of the Total …, 2013 - Elsevier
Parabens have been used in multiple products including personal care products,
pharmaceuticals, and foods for more than 50 years but increasing numbers of studies have …

Impacts of bisphenol A (BPA) and phthalate exposures on epigenetic outcomes in the human placenta

RS Strakovsky, SL Schantz - Environmental epigenetics, 2018 - academic.oup.com
The placenta guides fetal growth and development. Bisphenol A (BPA) and phthalates are
widespread environmental contaminants and endocrine disruptors, and the placental …

Environmental factors involved in maternal morbidity and mortality

AL Boyles, BE Beverly, SE Fenton… - Journal of Women's …, 2021 - liebertpub.com
Nongenetic, environmental factors contribute to maternal morbidity and mortality through
chemical exposures via air, water, soil, food, and consumer products. Pregnancy represents …

'Fetal side'of the placenta: anatomical mis-annotation of carbon particle 'transfer'across the human placenta

B Holder, JD Aplin, N Gomez-Lopez… - Nature …, 2021 - nature.com
In utero exposure to environmental agents is a critical driver of diseases manifesting in
childhood and adulthood 1, 2, and direct fetal contact with potentially harmful substances is …

Placental inflammatory cytokines mRNA expression and preschool children's cognitive performance: a birth cohort study in China

J Zhou, J Tong, X Ru, Y Teng, M Geng, S Yan, F Tao… - BMC medicine, 2023 - Springer
Background The immunologic milieu at the maternal–fetal interface has profound effects on
propelling the development of the fetal brain. However, accessible epidemiological studies …

Placental outcomes of phthalate exposure

GR Warner, RS Dettogni, IC Bagchi, JA Flaws… - Reproductive …, 2021 - Elsevier
Proper placental development and function relies on hormone receptors and signaling
pathways that make the placenta susceptible to disruption by endocrine disrupting …