Identifying drug targets plays essential roles in designing new drugs and combating
diseases. Unfortunately, our current knowledge about drug targets is far from …

Discovering and accurately locating drug targets is of great significance for the research and
development of new drugs. As a different approach to traditional drug development, the …

Diabetic nephropathy (DN), a common complication of diabetes mellitus, is the main cause
of end-stage nephropathy, and thus developing novel strategies for reversing DN remains …

Multiple sclerosis is an immune-mediated inflammatory disease of the central nervous
system characterised by demyelination, neuroaxonal loss and a heterogeneous clinical …

Knowledge of drug–target interaction (DTI) plays an important role in discovering new drug
candidates. Unfortunately, there are unavoidable shortcomings; including the time …

Motivation: Identifying drug–target protein interaction is a crucial step in the process of drug
research and development. Wet-lab experiment are laborious, time-consuming and …

Non-small cell lung cancer with an activating epidermal growth factor receptor (EGFR)
mutation responds well to targeted drugs. In most cases, drug resistance appears after about …

The target based drug design approaches are a series of computational procedures,
including visualization tools, to support the decision systems of drug design/discovery …

A rare disease refers to any disease with very low prevalence individually. Although the
impacted population is small for a single disease, more than 6000 rare diseases affect …

Biological targets are most commonly proteins such as enzymes, ion channels, and
receptors. They are anything within a living organism to bind with some other entities (like an …