Neuron–glia interaction in the Drosophila nervous system

J Bittern, N Pogodalla, H Ohm, L Brüser… - Developmental …, 2021 - Wiley Online Library
Animals are able to move and react in manifold ways to external stimuli. Thus,
environmental stimuli need to be detected, information must be processed, and, finally, an …

[HTML][HTML] A role for glia in cellular and systemic metabolism: insights from the fly

JF De Backer, ICG Kadow - Current Opinion in Insect Science, 2022 - Elsevier
Highlights•Drosophila glia share many properties with their mammalian
counterparts.•Different subpopulations of glia cells cooperate to support neuronal energy …

Cortical astrocytes regulate ethanol consumption and intoxication in mice

EK Erickson, AJ DaCosta, SC Mason… - …, 2021 - nature.com
Astrocytes are fundamental building blocks of the central nervous system. Their dysfunction
has been implicated in many psychiatric disorders, including alcohol use disorder, yet our …

A novel immune modulator IM33 mediates a glia-gut-neuronal axis that controls lifespan

W Xu, J Rustenhoven, CA Nelson, T Dykstra, A Ferreiro… - Neuron, 2023 - cell.com
Aging is a complex process involving various systems and behavioral changes. Altered
immune regulation, dysbiosis, oxidative stress, and sleep decline are common features of …

Flying Together: Drosophila as a Tool to Understand the Genetics of Human Alcoholism

DR Lathen, CB Merrill, A Rothenfluh - International journal of molecular …, 2020 - mdpi.com
Alcohol use disorder (AUD) exacts an immense toll on individuals, families, and society.
Genetic factors determine up to 60% of an individual's risk of developing problematic alcohol …

Glia‐specific expression of neuropeptide receptor Lgr4 regulates development and adult physiology in Drosophila

H Miao, Y Wei, SG Lee, Z Wu, J Kaur… - Journal of …, 2024 - Wiley Online Library
Similar to the human brain, Drosophila glia may well be divided into several subtypes that
each carries out specific functions. Glial GPCRs play key roles in crosstalk between neurons …

Identification of additional dye tracers for measuring solid food intake and food preference via consumption-excretion in Drosophila

BC Shell, M Grotewiel - Scientific Reports, 2022 - nature.com
The Drosophila model has become a leading platform for investigating mechanisms that
drive feeding behavior and the effect of diet on physiological outputs. Several methods for …

Looking at the Pretty “Phase” of Membraneless Organelles: A View From Drosophila Glia

AL Arkov - Frontiers in cell and developmental biology, 2022 - frontiersin.org
Membraneless granules assemble in different cell types and cellular loci and are the focus
of intense research due to their fundamental importance for cellular organization. These …

Tyramine synthesis, vesicular packaging, and the SNARE complex function coordinately in astrocytes to regulate Drosophila alcohol sedation

KM Lee, A Talikoti, K Shelton, M Grotewiel - Addiction biology, 2021 - Wiley Online Library
Identifying mechanisms underlying alcohol‐related behaviors could provide important
insights regarding the etiology of alcohol use disorder. To date, most genetic studies on …

The foraging gene affects alcohol sensitivity, metabolism and memory in Drosophila

AS Oepen, JL Catalano, R Azanchi… - Journal of …, 2021 - Taylor & Francis
The genetic basis of alcohol use disorder (AUD) is complex. Understanding how natural
genetic variation contributes to alcohol phenotypes can help us identify and understand the …