Genetic variability in humans is influenced by many factors, such as natural selection,
mutations, genetic drift, and migrations. Molecular epidemiology evaluates the contribution …

Multiple endocrine neoplasia type 2 (MEN2) is a neuroendocrine cancer syndrome
characterized by medullary thyroid carcinoma, in combination or not with …

Objective Twenty years ago, the groundbreaking discovery that rearranged during
transfection (RET) mutations underlie multiple endocrine neoplasia 2 (MEN2) and familial …

Background: Germline mutations of the RE arranged during T ransfection (RET) proto-
oncogene cause multiple endocrine neoplasia 2 (MEN2). It is unclear whether the …

Pheochromocytomas (PCCs) are rare neuroendocrine tumors that originate from chromaffin
cells of the adrenal medulla, and paragangliomas (PGLs) are extra-adrenal …

Background: Data on psychological harm in multiple endocrine neoplasia type 2 (MEN2) are
scarce. Objectives: The aim of this study was to assess anxiety, depression, quality of life …

Background Germline RET mutations and variants are involved in development of multiple
endocrine neoplasia type 2 (MEN2). The present study investigated a spectrum of RET …

Introduction Early and normative surgery is the only curative method for multiple endocrine
neoplasia type 2 (MEN 2)-related medullary thyroid carcinoma (MTC). Aims To study the …

Background: Mixed medullary and follicular thyroid carcinoma (MMFC) displays
heterogeneous morphological components and immunophenotypical features intermingled …

Background Hereditary medullary thyroid carcinoma can present as a part of multiple
endocrine neoplasia syndrome by rearranged during transfection gene mutation. We …