Interaction of nanoparticles with cells

V Mailander, K Landfester - Biomacromolecules, 2009 - ACS Publications
Nanoparticles and their interaction with human cells have been a focus of many groups
during the past decade. We discuss and review here the progress in the field of …

Computational modeling for the design and development of nano based drug delivery systems

T Ashwini, R Narayan, PA Shenoy, UY Nayak - Journal of Molecular Liquids, 2022 - Elsevier
The nanoparticle delivery system is one of the promising nanotechnology applications for
efficient drug delivery to the targeted site. However, the selection of lead excipient …

Uptake of functionalized, fluorescent-labeled polymeric particles in different cell lines and stem cells

MR Lorenz, V Holzapfel, A Musyanovych, K Nothelfer… - Biomaterials, 2006 - Elsevier
Labeling of cells with particles for in-vivo detection is interesting for various biomedical
applications. The objective of this study was to evaluate the feasibility and efficiency labeling …

Whole-body physiologically based pharmacokinetic models

I Nestorov - Expert opinion on drug metabolism & toxicology, 2007 - Taylor & Francis
This review summarizes the most recent developments in and applications of physiologically
based pharmacokinetic (PBPK) modeling methodology originating from both the …

Toward a general physiologically-based pharmacokinetic model for intravenously injected nanoparticles

U Carlander, D Li, O Jolliet, C Emond… - International journal of …, 2016 - Taylor & Francis
To assess the potential toxicity of nanoparticles (NPs), information concerning their uptake
and disposition (biokinetics) is essential. Experience with industrial chemicals and …

Synthesis and characterization of carboxymethyl dextran-coated Mn/Zn ferrite for biomedical applications

M Latorre-Esteves, A Cortes, M Torres-Lugo… - Journal of Magnetism …, 2009 - Elsevier
Previous studies have shown that magnetic nanoparticles possess great potential for
various in vivo applications such as magnetic resonance imaging contrast enhancement …

[HTML][HTML] Physiologically based mathematical models of nanomaterials for regulatory toxicology: A review

L Lamon, D Asturiol, A Vilchez, J Cabellos… - Computational …, 2019 - Elsevier
The development of physiologically based (PB) models to support safety assessments in the
field of nanotechnology has grown steadily during the last decade. This review reports on …

Parenteral emulsions and liposomes to treat drug overdose

R Damitz, A Chauhan - Advanced Drug Delivery Reviews, 2015 - Elsevier
Drug overdoses from both pharmaceutical and recreational drugs are a major public health
concern. Although some overdoses may be treated with specific antidotes, the most common …

Hemostasis disorders caused by polymer coated iron oxide nanoparticles

L Ali, M Gutiérrez, R Cornudella… - Journal of …, 2013 - ingentaconnect.com
Background. Superparamagnetic iron oxide nanoparticles (SPIONs) are inorganic
nanomaterials gaining strong clinical interest due to their increasing number of biological …

Pharmacokinetics and physiologically-based pharmacokinetic modeling of nanoparticles

RSH Yang, LW Chang, CS Yang… - Journal of nanoscience …, 2010 - ingentaconnect.com
The worldwide commerce involving nanoparticles will soon reach $1 trillion and already we
have more than 600 commercial products containing nanoparticles. Because nanoparticles …