Long non-coding RNAs and microRNAs interplay in osteogenic differentiation of mesenchymal stem cells

C Lanzillotti, M De Mattei, C Mazziotta… - Frontiers in Cell and …, 2021 - frontiersin.org
Long non-coding RNAs (lncRNAs) have gained great attention as epigenetic regulators of
gene expression in many tissues. Increasing evidence indicates that lncRNAs, together with …

Mesenchymal stem cells and extracellular vesicles in osteosarcoma pathogenesis and therapy

VK Sarhadi, R Daddali… - International journal of …, 2021 - mdpi.com
Osteosarcoma (OS) is an aggressive bone tumor that mainly affects children and
adolescents. OS has a strong tendency to relapse and metastasize, resulting in poor …

Additively manufactured 316L stainless steel with improved corrosion resistance and biological response for biomedical applications

MJK Lodhi, KM Deen, MC Greenlee-Wacker… - Additive …, 2019 - Elsevier
Enhancing the corrosion resistance and improving the biological response to 316 L
stainless steel is a long-standing and active area of biomedical research. Here, we analyzed …

[HTML][HTML] Extracellular matrix dynamics during mesenchymal stem cells differentiation

T Assis-Ribas, MF Forni, SMB Winnischofer… - Developmental …, 2018 - Elsevier
Mesenchymal stem cells (MSCs) are stromal cells that display self-renewal and multipotent
differentiation capacity. The repertoire of mature cells generated ranges but is not restricted …

Multipotent mesenchymal stem cell-based therapies for spinal cord injury: current progress and future prospects

CW Zeng - Biology, 2023 - mdpi.com
Simple Summary Mesenchymal stem cells (MSCs) are a promising option for developing
new treatments for spinal cord injury (SCI). They can help repair damaged tissue, making …

Proteoglycans and glycosaminoglycans in stem cell homeostasis and bone tissue regeneration

J Chen, T Sun, Y You, B Wu, X Wang… - Frontiers in Cell and …, 2021 - frontiersin.org
Stem cells maintain a subtle balance between self-renewal and differentiation under the
regulatory network supported by both intracellular and extracellular components …

[HTML][HTML] High-depth transcriptomic profiling reveals the temporal gene signature of human mesenchymal stem cells during chondrogenesis

NPT Huynh, B Zhang, F Guilak - The FASEB Journal, 2018 - pmc.ncbi.nlm.nih.gov
Mesenchymal stem/stromal cells (MSCs) provide an attractive cell source for cartilage repair
and cell therapy; however, the underlying molecular pathways that drive chondrogenesis of …

Gene expression profiling of chondrogenic differentiation by dexamethasone-conjugated polyethyleneimine with SOX trio genes in stem cells

SW Yi, HJ Kim, HJ Oh, H Shin, JS Lee, JS Park… - Stem Cell Research & …, 2018 - Springer
Background During differentiation of stem cells, it is recognized that molecular mechanisms
of transcription factors manage stem cells towards the intended lineage. In this study, using …

The roles of exosomes in metastasis of sarcoma: from biomarkers to therapeutic targets

L Tan, Y Wang, X Hu, L Min - Biomolecules, 2023 - mdpi.com
Sarcoma is a heterogeneous group of mesenchymal neoplasms with a high rate of lung
metastasis. The cellular mechanisms responsible for sarcoma metastasis remain poorly …

CircSmg5 stimulates the osteogenic differentiation of bone marrow mesenchymal stem cells by targeting the miR‐194‐5p/Fzd6 axis and beta‐catenin signaling

Y Lu, YK Liu, FY Wan, S Shi, R Tao - Environmental toxicology, 2022 - Wiley Online Library
Background Osteogenic differentiation of bone marrow mesenchymal stem cells (BMSCs) is
closely associated with bone diseases. Circular RNAs are reported to be involved in BMSC …