Galectins are a family of animal lectins that bind β-galactosides. Outside the cell, galectins
bind to cell-surface and extracellular matrix glycans and thereby affect a variety of cellular …

Galectins are widely distributed sugar-binding proteins whose basic specificity for β-
galactosides is conserved by evolutionarily preserved carbohydrate-recognition domains …

GALECTIN-1, a member of the family of β-galactoside binding proteins1, has growth
regulatory and immunomodulatory activities2–4. We report here that galectin-1, expressed …

Galectins, which were first characterized in the mid-1970s, were assigned a role in the
recognition of endogenous ('self') carbohydrate ligands in embryogenesis, development and …

The number of glycan determinants that comprise the human glycome is not known. This
uncertainty arises from limited knowledge of the total number of distinct glycans and glycan …

The fact that natural β-sheet proteins are usually soluble but that fragments or designs of β
structure usually aggregate suggests that natural β proteins must somehow be designed to …

The legume lectins are a large family of homologous carbohydrate binding proteins that are
found mainly in the seeds of most legume plants. Despite their strong similarity on the level …

Galectins are a family of mammalian β-galactoside-binding proteins that positively and
negatively regulate T cell death. Extracellular galectin-1 directly induces death of T cells and …

In the past decade, increasing efforts have been devoted to the study of galectins, a family of
evolutionarily conserved glycan-binding proteins with multifunctional properties. Galectins …

This is the second edition of our little red book Lectins published in 1989. In the intervening
years well over 10,000 articles have appeared with lectins as the main subject, and more …