Nano-drug co-delivery system of natural active ingredients and chemotherapy drugs for cancer treatment: a review

B Li, H Shao, L Gao, H Li, H Sheng, L Zhu - Drug Delivery, 2022 - Taylor & Francis
Chemotherapy drugs have been used for a long time in the treatment of cancer, but serious
side effects are caused by the inability of the drug to be solely delivered to the tumor when …

Doxil®—The first FDA-approved nano-drug: Lessons learned

YC Barenholz - Journal of controlled release, 2012 - Elsevier
Doxil®, the first FDA-approved nano-drug (1995), is based on three unrelated principles:(i)
prolonged drug circulation time and avoidance of the RES due to the use of PEGylated nano …

Liposome-based drug co-delivery systems in cancer cells

SZ Vahed, R Salehi, S Davaran, S Sharifi - Materials Science and …, 2017 - Elsevier
Combination therapy and nanotechnology offer a promising therapeutic method in cancer
treatment. By improving drug's pharmacokinetics, nanoparticulate systems increase the …

Extracellular vesicles as drug delivery systems: lessons from the liposome field

R van der Meel, MHAM Fens, P Vader… - Journal of controlled …, 2014 - Elsevier
Extracellular vesicles (EVs) are membrane-derived particles surrounded by a (phospho)
lipid bilayer that are released by cells in the human body. In addition to direct cell-to-cell …

Herbal nanomedicines: Recent advancements, challenges, opportunities and regulatory overview

PK Teja, J Mithiya, AS Kate, K Bairwa, SK Chauthe - Phytomedicine, 2022 - Elsevier
Abstract Background Herbal Nano Medicines (HNMs) are nano-sized medicine containing
herbal drugs as extracts, enriched fractions or biomarker constituents. HNMs have certain …

Drug nanocrystallisation within liposomes

T Li, D Cipolla, T Rades, BJ Boyd - Journal of Controlled Release, 2018 - Elsevier
Liposomes are phospholipid bilayer vesicles that have been explored in pharmaceutical
research as drug delivery systems for> 50 years. Despite being important to their …

Polymer-drug conjugate, a potential therapeutic to combat breast and lung cancer

S Alven, X Nqoro, B Buyana, BA Aderibigbe - Pharmaceutics, 2020 - mdpi.com
Cancer is a chronic disease that is responsible for the high death rate, globally. The
administration of anticancer drugs is one crucial approach that is employed for the treatment …

Benefits and limitations of nanomedicine treatment of brain cancers and age-dependent neurodegenerative disorders

ME Neganova, YR Aleksandrova… - Seminars in Cancer …, 2022 - Elsevier
The treatment of central nervous system (CNS) malignancies, including brain cancers, is
limited by a number of obstructions, including the blood-brain barrier (BBB), the …

Co-delivery of camptothecin and curcumin by cationic polymeric nanoparticles for synergistic colon cancer combination chemotherapy

B Xiao, X Si, MK Han, E Viennois, M Zhang… - Journal of materials …, 2015 - pubs.rsc.org
Nanoparticle (NP)-based combination chemotherapy has been proposed as a potent
strategy for enhancing intracellular drug concentrations and achieving synergistic effects in …

Synergistic co-loading of vincristine improved chemotherapeutic potential of pegylated liposomal doxorubicin against triple negative breast cancer and non-small cell …

S Ghosh, R Lalani, K Maiti, S Banerjee, H Bhatt… - … , Biology and Medicine, 2021 - Elsevier
The current work aims to explore the biological characteristics of vincristine synergistic co-
loading into pegylated liposomal doxorubicin in non-indicated modalities of non-small cell …