Excessive scar formation is a hallmark of localized and systemic fibrotic disorders. Despite
extensive studies to define valid anti-fibrotic targets and develop effective therapeutics …

Lysyl oxidase (LOX) is an enzyme that oxidizes lysine residues in collagens and elastin. It
stabilizes or remodels the extracellular matrix and basement membrane of blood vessels …

Objective This study aimed to establish a rat model that simulates benign esophageal
strictures induced by endoscopic submucosal dissection (ESD). Materials and Methods …

BACKGROUND: Corrosive esophageal burns, particularly common in developing countries,
lead to different problems in different age groups. The ingestion of corrosive substances can …

Ingestion of a corrosive substance may cause corrosive esophagitis. Curcumin has anti-
inflammatory and mucosal protective effects. In this study, the effects of curcumin on the …

Lysyl oxidase (LOX) serves an important role in remodeling the extracellular matrix and
angiogenesis in various types of cancer; however, whether LOX is involved in the …

ABSTRACT BACKGROUND: In developing countries, esophageal burns are quite common.
They are caused by the ingestion of corrosive substances that may lead to esophageal …

Purpose To investigate the efficacy of cordycepin, an adenosine analogue, on prevention of
esophageal damage and stricture formation due to esophageal caustic burns in rat model …

Although oxaliplatin (Oxali) plays a key role in the treatment of many types of cancer and has
been reported to be an irritant, there is no specific and effective method for its extravasation …

Актуальность проблемы. Острые химические повреждения верхнего отдела желудочно-
кишечного тракта в России занимают третье место в структуре острой химической …