Recent years have seen an increased understanding of the importance of myelination in
healthy brain function and neuropsychiatric diseases. Non-invasive microstructural magnetic …

Myelin is critical for healthy brain function. An accurate in vivo measure of myelin content
has important implications for understanding brain plasticity and neurodegenerative …

Multiexponential T2 relaxation time measurement in the central nervous system shows a
component that originates from water trapped between the lipid bilayers of myelin. This …

Magnetization transfer contrast has yielded insight into brain tissue microstructure changes
across the lifespan and in a range of disorders. This progress has been aided by the …

Myelin is important for the normal development and healthy function of the nervous system.
Recent developments in MRI acquisition and tissue modeling aim to provide a better …

MRI relaxometry is sensitive to a variety of tissue characteristics in a complex manner, which
makes it both attractive and challenging for characterizing tissue. This article reviews the …

Magnetization transfer (MT) imaging has been widely used for estimating myelin content in
the brain. Recently, two other approaches, namely simultaneous tissue relaxometry of R1 …

The fiber g-ratio is the ratio of the inner to the outer diameter of the myelin sheath of a
myelinated axon. It has a limited dynamic range in healthy white matter, as it is optimized for …

Characterizing demyelination/degeneration of spinal pathways in traumatic spinal cord
injured (SCI) patients is crucial for assessing the prognosis of functional rehabilitation. Novel …

Names: Cercignani, Mara, editor.| Dowell, Nicholas G., editor.| Tofts, Paul S., editor. Title:
Quantitative MRI of the brain: principles of physical measurement/editors, Mara Cercignani …