This review focuses on neuropeptides and peptide hormones, the largest and most diverse
class of neuroactive substances, known in Drosophila and other animals to play roles in …

The control of body and organ growth is essential for the development of adults with proper
size and proportions, which is important for survival and reproduction. In animals, adult body …

Insulin, insulin-like growth factors (IGFs) and insulin-like peptides (ILPs) are important
regulators of metabolism, growth, reproduction and lifespan, and mechanisms of insulin/IGF …

Lipid metabolism is fundamental to life. In insects, it is critical, during reproduction, flight,
starvation, and diapause. The coordination center for insect lipid metabolism is the fat body …

The insulin-like peptide (ILP) and insulin-like growth factor (IGF) signalling pathways play a
crucial role in the regulation of metabolism, growth and development, fecundity, stress …

Plasticity in animal behaviour relies on the ability to integrate external and internal cues from
the changing environment and hence modulate activity in synaptic circuits of the brain. This …

Taking advantage of Drosophila as a genetically tractable experimental animal much
progress has been made in our understanding of how the insulin/IGF signaling (IIS) pathway …

Hunger is a motivational state that drives eating and food-seeking behaviour. In a
psychological sense, hunger sets the goal that guides an animal in the pursuit of food. The …

Growth is a complex process that is intimately linked to the developmental program to form
adults with proper size and proportions. Genetics is an important determinant of growth, as …

The Serotonin Transporter (SERT) regulates extracellular serotonin levels and is the target
of most current drugs used to treat depression. The mechanisms by which inhibition of SERT …