Focal therapy is a modern alternative to selectively treat a specific part of the prostate
harboring clinically significant disease while preserving the rest of the gland. The aim of this …

This article reviews the most current methods and technological aspects of high‐intensity
focused ultrasound (HIFU), which is termed histotripsy. The rationale for focal therapy for …

Background To reduce adverse effects of whole-gland therapy, participants with localized
clinically significant prostate cancer can undergo MRI-guided focal therapy. Purpose To …

Background MRI-guided focal therapy (FT) allows for accurate targeting of localized
clinically significant prostate cancer (csPCa) while preserving healthy prostate tissue, but the …

Purpose To define the role of focal laser ablation (FLA) as clinical treatment of prostate
cancer (PCa) using the Delphi consensus method. Methods A panel of international experts …

Objectives To assess change in functional outcomes after a second focal high‐intensity
focused ultrasonography (HIFU) treatment compared with outcomes after one focal HIFU …

High-intensity focused ultrasound (HIFU) was experimentally used for focal therapy for anti-
cancer effects in prostate cancer (PC). Focal therapy is a diagnosis-based investigational …

LUTS can be in the form of stress urinary incontinence (SUI), urge urinary incontinence
(UUI), frequency/urgency, and/or voiding difficulties. While surgery is mostly associated with …

Background The oncological outcomes in men with clinically significant prostate cancer
following focal cryotherapy are promising, although functional outcomes are under-reported …

Patients with primary localised prostate cancer (PCa) have a wide choice of curative
therapeutic interventions, including active surveillance, surgical, focal and radiation …