Cellular and molecular mechanisms of curcumin in prevention and treatment of disease

SS Patel, A Acharya, RS Ray, R Agrawal… - Critical reviews in …, 2020 - Taylor & Francis
Curcumin is a naturally occurring polyphenolic compound present in rhizome of Curcuma
longa belonging to the family zingiberaceae. Growing experimental evidence revealed that …

Hormones and oxidative stress: an overview

GBN Chainy, DK Sahoo - Free Radical Research, 2020 - Taylor & Francis
In aerobes, oxygen is essential for maintenance of life. However, incomplete reduction of
oxygen leads to generation of reactive oxygen species. These oxidants oxidise biological …

Protective effect of curcumin against heavy metals-induced liver damage

WR García-Niño, J Pedraza-Chaverrí - Food and chemical toxicology, 2014 - Elsevier
Occupational or environmental exposures to heavy metals produce several adverse health
effects. The common mechanism determining their toxicity and carcinogenicity is the …

Recent developments in curcumin and curcumin based polymeric materials for biomedical applications: A review

K Mahmood, KM Zia, M Zuber, M Salman… - International journal of …, 2015 - Elsevier
Turmeric (Curcuma longa) is a popular Indian spice that has been used for centuries in
herbal medicines for the treatment of a variety of ailments such as rheumatism, diabetic …

The role of thyroid hormones as inductors of oxidative stress and neurodegeneration

I Villanueva, C Alva-Sánchez… - … medicine and cellular …, 2013 - Wiley Online Library
Reactive oxygen species (ROS) are oxidizing agents amply implicated in tissue damage.
ROS production is inevitably linked to ATP synthesis in most cells, and the rate of production …

Curcumin-loaded PLA-PEG copolymer nanoparticles for treatment of liver inflammation in streptozotocin-induced diabetic rats

ME El-Naggar, F Al-Joufi, M Anwar, MF Attia… - Colloids and Surfaces B …, 2019 - Elsevier
This report focused on loading curcumin (CUR) drug into biodegradable Polylactide-poly
(ethylene glycol)(PLA-PEG) copolymer nanoparticles as an effective anti-inflammatory agent …

Chronic chlorpyrifos exposure induces oxidative stress, apoptosis and immune dysfunction in largemouth bass (Micropterus salmoides)

L Zhao, G Tang, C Xiong, S Han, C Yang, K He… - Environmental …, 2021 - Elsevier
This study was undertaken to (a) evaluate the destructive effects of chronic exposure to low-
dose of chlorpyrifos (CPF) on antioxidant system and immune function in largemouth bass …

Curcumin prevents Cr (VI)-induced renal oxidant damage by a mitochondrial pathway

E Molina-Jijón, E Tapia, C Zazueta, M El Hafidi… - Free Radical Biology …, 2011 - Elsevier
We report the role of mitochondria in the protective effects of curcumin, a well-known direct
and indirect antioxidant, against the renal oxidant damage induced by the hexavalent …

Improvement in oxidative stress and antioxidant parameters in β-thalassemia/Hb E patients treated with curcuminoids

RW Kalpravidh, N Siritanaratkul, P Insain… - Clinical …, 2010 - Elsevier
OBJECTIVES: To evaluate the hematological profile, oxidative stress, and antioxidant
parameters in β-thalassemia/Hb E patients treated with curcuminoids for 12 months …

Influence of thyroid dysfunction on liver lipid peroxidation and antioxidant status in experimental rats

M Messarah, A Boumendjel, A Chouabia… - Experimental and …, 2010 - Elsevier
The purpose of this study was to evaluate the effects of dysthyroidism on lipid peroxidation,
antioxidants status, liver, and serum dysfunction parameters in the hypo-/hyperthyroidism …