Open fractures are often associated with high-energy trauma and have an increased risk of
infection because of surrounding soft-tissue damage and the introduction of environmental …

Infection is a common cause of impaired fracture healing. In the clinical setting, definitive
fracture treatment and infection are often treated separately and sequentially, by different …

Elimination of infection and enhancement of osteogenesis by orthopaedic implants are two
critical factors in the treatment of complex bone infections. A prolonged and expensive …

Soft tissue infections in open fractures or burns are major cause for high morbidity in trauma
patients. Sustained, long-term and localized delivery of antimicrobial agents is needed for …

Methods: Following the Preferred Reporting Items for Systematic Reviews and Meta-
Analyses guidelines, electronic searches were conducted on Ovid MEDLINE, and PubMed …

Objective: Evaluate the species distribution and resistance patterns of bacterial pathogens
causing surgical site infection (SSI) after operative fracture repair, with and without the use of …

This study aims to elaborate the relevance of trauma severity and traumatic injury pattern in
different multiple and/or polytrauma models by comparing five singular trauma to two …

Background The glycopeptide antibiotics are a class of antimicrobial drugs that are an
important alternative for cases of bacterial infections resistant to penicillins, besides being …

Aims: To develop and validate a new ecological HPLC method for the determination of
vancomycin dosage form. Background: Vancomycin is an important antimicrobial. According …

Background: Open fractures are at high risk for complications both in the military and civilian
setting. Treatments to prevent fractures are limited in the Role 1 (prehospital, battalion aid …