Uveal melanoma (UM) is a global disease which especially occurs in elderly people. Its
incidence varies widely between populations, with the highest incidence among …

This assessment by the Environmental Effects Assessment Panel (EEAP) of the Montreal
Protocol under the United Nations Environment Programme (UNEP) evaluates the effects of …

Conjunctival melanoma (CM) is a rare but aggressive cancer. Over the past decade,
molecular studies using rapidly advancing technologies have increasingly improved our …

Background Genomic characterisation has led to an improved understanding of adult
melanoma. However, the aetiology of melanoma in children is still unclear and identifying …

Background CD8+ T cells work as a key effector of adaptive immunity and are closely
associated with immune response for killing tumor cells. It is crucial to understand the role of …

Simple Summary Uveal melanoma (UM) is the most common form of eye cancer in adults. It
has a poor prognosis and limited treatment options. UM, unlike cutaneous melanoma (CM) …

Mutations in ARID2 and TP53 genes are found to be implicated in the tobacco related
tumorigeneses. However, the effect of loss of ARID2 in the TP53 mutated background in …

Uveal melanoma (UVM) is a highly aggressive ocular cancer with limited therapeutic options
and poor prognosis particularly for patients with liver metastasis. As such, the identification …

Abstract Background/Objectives Iris melanoma, a rare intraocular malignancy, represents
the smallest subgroup of uveal melanoma. This first, comprehensive study of iris melanocytic …

Simple Summary Uveal melanoma (UM) is a rare form of melanoma originating in the eye.
Unlike cutaneous melanoma (CM), the role of ultraviolet radiation (UVR) in UM aetiology is …