This review discusses advances in the field of ambient sampling/ionization mass
spectrometry (“ambient MS” for short) with a focus on mechanistic and instrumentation …

Thin-layer chromatography–matrix-assisted laser desorption and ionization mass
spectrometry (TLC–MALDI-MS) of organic extracts from biological samples allows …

In this review we highlight the general change in perception in the field of ambient mass
spectrometry that it is the immediacy of sample preparation that differentiates the ambient …

Integration of multiomics at the single-cell level allows the unambiguous dissecting of
phenotypic heterogeneity at different states such as health, disease, and biomedical …

Microorganisms such as bacteria and fungi produce a variety of specialized metabolites that
are invaluable for agriculture, biological research, and drug discovery. However, the …

RATIONALE A continuous‐flow liquid microjunction surface sampling probe extracts soluble
material from surfaces for direct ionization and detection by mass spectrometry …

Tissue spatially-resolved proteomics was performed on 3 brain regions, leading to the
characterization of 123 reference proteins. Moreover, 8 alternative proteins from alternative …

Liquid extraction surface analysis (LESA) mass spectrometry is a promising tool for the
analysis of intact proteins from biological substrates. Here, we demonstrate native LESA …

The rapid and direct analysis of the amount and spatial distribution of exogenous
chloroquine (CHQ) and CHQ metabolites from tissue sections by liquid extraction surface …

Mass spectrometry (MS)-based microproteomics on localized regions of tissue sections was
achieved by direct coupling of liquid microjunction microextraction with a nanoscale liquid …