Clinical applications of hallucinogens: A review.

A Garcia-Romeu, B Kersgaard… - Experimental and clinical …, 2016 - psycnet.apa.org
Hallucinogens fall into several different classes, as broadly defined by pharmacological
mechanism of action, and chemical structure. These include psychedelics, entactogens …

Psychedelics as medicines for substance abuse rehabilitation: evaluating treatments with LSD, Peyote, Ibogaine and Ayahuasca

M Winkelman - Current drug abuse reviews, 2014 - ingentaconnect.com
Substances known as psychedelics, hallucinogens and entheogens have been employed in
ethnomedical traditions for thousands of years, but after promising uses in the 1950's and …

A non-hallucinogenic psychedelic analogue with therapeutic potential

LP Cameron, RJ Tombari, J Lu, AJ Pell, ZQ Hurley… - Nature, 2021 - nature.com
The psychedelic alkaloid ibogaine has anti-addictive properties in both humans and animals
1. Unlike most medications for the treatment of substance use disorders, anecdotal reports …

Psychedelic-assisted psychotherapy: A paradigm shift in psychiatric research and development

EE Schenberg - Frontiers in pharmacology, 2018 - frontiersin.org
Mental disorders are rising while development of novel psychiatric medications is declining.
This stall in innovation has also been linked with intense debates on the current diagnostics …

Treatment of opioid use disorder with ibogaine: detoxification and drug use outcomes

TK Brown, K Alper - The American Journal of Drug and Alcohol …, 2018 - Taylor & Francis
Background: Ibogaine is a monoterpene indole alkaloid used in medical and nonmedical
settings for the treatment of opioid use disorder. Its mechanism of action is apparently novel …

Ibogaine treatment outcomes for opioid dependence from a twelve-month follow-up observational study

GE Noller, CM Frampton… - The American journal of …, 2018 - Taylor & Francis
Background: The psychoactive indole alkaloid ibogaine has been associated with
encouraging treatment outcomes for opioid dependence. The legal status of ibogaine in …

[HTML][HTML] A systematic literature review of clinical trials and therapeutic applications of ibogaine

P Köck, K Froelich, M Walter, U Lang… - Journal of Substance …, 2022 - Elsevier
Background Iboga and its primary alkaloids, ibogaine and noribogaine, have been of
interest to researchers and practitioners, mainly due to their putative efficacy in treating …

The iboga enigma: the chemistry and neuropharmacology of iboga alkaloids and related analogs

RN Iyer, D Favela, G Zhang, DE Olson - Natural product reports, 2021 - pubs.rsc.org
Covering: 2000 up to 2020 Few classes of natural products have inspired as many chemists
and biologists as have the iboga alkaloids. This family of monoterpenoid indole alkaloids …

[HTML][HTML] Ibogaine detoxification transitions opioid and cocaine abusers between dependence and abstinence: clinical observations and treatment outcomes

DC Mash, L Duque, B Page - Frontiers in pharmacology, 2018 - frontiersin.org
Ibogaine may be effective for transitioning opioid and cocaine dependent individuals to
sobriety. American and European self-help groups provided public testimonials that …

The anti-addiction drug ibogaine and the heart: a delicate relation

X Koenig, K Hilber - Molecules, 2015 - mdpi.com
The plant indole alkaloid ibogaine has shown promising anti-addictive properties in animal
studies. Ibogaine is also anti-addictive in humans as the drug alleviates drug craving and …