Diagnosis and management of hepatic encephalopathy

M Rudler, N Weiss, C Bouzbib… - Clinics in liver disease, 2021 - liver.theclinics.com
The prevalence and cumulative incidence of hepatic encephalopathy (HE) are difficult to
state precisely. Thirty percent to 45% of cirrhotic patients could be affected by overt hepatic …

Neurological Wilson's Disease Signs—Hepatic Encephalopathy or Copper Toxicosis?

A Jopowicz, B Tarnacka - Diagnostics, 2023 - mdpi.com
Wilson's disease (WD) is a rare autosomal recessive (AR) disorder resulting from mutations
in the ATP7B gene, which is responsible for the encryption of transmembrane copper …

Meta-analysis of magnetic resonance spectroscopy in the diagnosis of hepatic encephalopathy

G Zeng, R Penninkilampi, J Chaganti, S Montagnese… - Neurology, 2020 - AAN Enterprises
Objective Various imaging modalities have been used to explore pathogenic mechanisms
and stratify the severity of hepatic encephalopathy (HE). The hypothesis of this meta …

[HTML][HTML] PET CMRglc mapping and 1H-MRS show altered glucose uptake and neurometabolic profiles in BDL rats

J Mosso, T Yin, C Poitry-Yamate, D Simicic… - Analytical …, 2022 - Elsevier
Type C hepatic encephalopathy (HE) is a complex neuropsychiatric disorder occurring as a
consequence of chronic liver disease. Alterations in energy metabolism have been …

Toxic-metabolic encephalopathy in adults: Critical discussion and pragmatical diagnostic approach

L Le Guennec, C Marois, S Demeret, EFM Wijdicks… - Revue …, 2022 - Elsevier
Toxic-metabolic encephalopathy (TME) results from an acute cerebral dysfunction due to
different metabolic disturbances including medications or illicit-drugs. It can lead to altered …

Metabolomics in the understanding and management of hepatic encephalopathy

J Pelle, FA Castelli, M Rudler, I Alioua, B Colsch… - Analytical …, 2022 - Elsevier
Metabolomics refers to the study of biological components below 1000 Daltons (Da)
involved in metabolic pathways as substrates, products or effectors. According to the …

J-difference GABA-edited MRS reveals altered cerebello-thalamo-cortical metabolism in patients with hepatic encephalopathy

HJ Zöllner, TA Thiel, ND Füllenbach, MS Jördens… - Metabolic brain …, 2023 - Springer
Hepatic encephalopathy (HE) is a common neurological manifestation of liver cirrhosis and
is characterized by an increase of ammonia in the brain accompanied by a disrupted …

Electroacupuncture Synergistically Inhibits Proinflammatory Cytokine Production and Improves Cognitive Function in Rats with Cognitive Impairment due to Hepatic …

J Huang, Z Gong, Y Kong, Y Huang… - Evidence‐Based …, 2021 - Wiley Online Library
Objective. To investigate the effect of electroacupuncture (EA) on cognitive dysfunction in
rats with hepatic encephalopathy and its underlying mechanism. Methods. Fifty Wistar rats …

[HTML][HTML] Intestinal Dysbacteriosis Contributes to Persistent Cognitive Impairment after Resolution of Acute Liver Failure

Z Li, T Sun, Z He, Z Li, J Xiong, H Xiang - The American Journal of …, 2024 - Elsevier
Regulating the gut microbiota alleviates hepatic encephalopathy (HE). Whether it is
imperative to withhold treatment for microbial imbalance after liver functional recovery …

[HTML][HTML] Novel magnetic resonance KTRANS measurement of blood-brain barrier permeability correlated with covert HE

J Chaganti, G Zeng, N Tun, I Lockart… - Hepatology …, 2023 - journals.lww.com
Background: Using dynamic contrast-enhanced (DCE) MR perfusion and MR spectroscopy
this study aimed to characterize the blood-brain barrier permeability and metabolite changes …