Rac1 is a small GTPase that belongs to the Rho family. The Rho family of small GTPases is
a subfamily of the Ras superfamily. The Rho family of GTPases mediate a plethora of …

Ran is a nucleocytoplasmic shuttle protein that is involved in cell cycle regulation, nuclear-
cytoplasmic transport, and cell transformation. Ran plays an important role in cancer cell …

The small GTPase RhoA has been implicated in various cellular activities, including the
formation of stress fibers, cell motility, and cytokinesis. In addition to the canonical GTPase …

During gene expression, multiple regulatory steps make sure that alterations of chromatin
structure are synchronized with RNA synthesis, co-transcriptional assembly of …

Background Neurite formation and synaptic patterning are fundamental to the development
of a functional nervous system. Flavonoids are natural molecules known for having …

RhoA, an extensively studied member of the Rho GTPase family, has been identified as a
mediator of pro-inflammatory responses and aggressive carcinogenesis. Bacterial …

Background Autotaxin (ATX) possesses lysophospholipase D (lyso PLD) activity, which
converts lysophosphatidylcholine (LPC) into lysophosphatidic acid (LPA). The ATX-LPA …

The aim of this study was to elucidate the localization of RhoA in human cancer tissues and
cancer cell lines. Immunohistochemistry and immunofluorescence microscopy were used to …

Gastric cancer (GC) is the second leading cause of death from cancer worldwide, with 5-
year survival rate for about 20% of the affected individuals. Although there is a decrease in …

The aim of the present study was to observe the influence of various factors on the nuclear
distribution of the RhoA protein in the SGC-7901 human gastric cancer cell line …