Metabolomics, an omic science in systems biology, is the global quantitative assessment of
endogenous metabolites within a biological system. Either individually or grouped as a …

The emerging field of metabolomics, in which a large number of small-molecule metabolites
from body fluids or tissues are detected quantitatively in a single step, promises immense …

Nuclear magnetic resonance (NMR) spectroscopy can be used to both identify and quantify
chemicals from complex mixtures. This can be done semi-automatically by comparing the …

An extraordinary new technique using hyperpolarized 13C-labeled pyruvate and taking
advantage of increased glycolysis in cancer has the potential to improve the way magnetic …

Early detection of prostate cancer (PC) is largely carried out using assessment of prostate-
specific antigen (PSA) level; yet it cannot reliably discriminate between benign pathologies …

Nuclear Magnetic Resonance (NMR) spectroscopy is a quantitative analytical tool
commonly utilized for metabolomics analysis. Quantitative NMR (qNMR) is a field of NMR …

Citrate is an important substrate in cellular energy metabolism. It is produced in the
mitochondria and used in the Krebs cycle or released into cytoplasm through a specific …

Metabolic profiling, metabolomic and metabonomic studies require robust study protocols for
any large-scale comparisons and evaluations. Detailed methods for solution-state NMR …

Separating indolent from aggressive prostate cancer is an important clinical challenge for
identifying patients eligible for active surveillance, thereby reducing the risk of overtreatment …

We have reviewed the main contributions to the development of NMR-based metabonomic
and metabolic profiling approaches for toxicological assessment, biomarker discovery, and …