[HTML][HTML] Green Catalysts and/or Green Solvents for Sustainable Multi-Component Reactions

G Messire, E Caillet, S Berteina-Raboin - Catalysts, 2024 - mdpi.com
Here, we describe some well-known multicomponent reactions and the progress made over
the past decade to make these processes even more environmentally friendly. We focus on …

A review on environment-friendly protocol for the synthesis of pyrazole derivative

N Kumar, S Rajput, R Patel, A Yadav… - Current Green …, 2024 - benthamdirect.com
Pyrazole derivatives are a significant group of heterocyclic compounds that have a diverse
variety of biological activities and are used in several fields, such as medicines …

[HTML][HTML] Electrochemical cascade pyrazole annulation and CH halogenation for the synthesis of 4-halopyrazoles

H Guo, Y Liu, JP Wan - Green Synthesis and Catalysis, 2023 - Elsevier
The synthesis of 4-halo-functionalized pyrazoles by electrochemical cascade reactions
between N, N-dimethyl enaminones and proper hydrazine reagents in the presence of a …

Study of physiochemical properties of trisubstituted pyrazole derivatives using polar aprotic solvents

P Devi, H Anand, R Pundeer, S Kumar - Scientific Reports, 2025 - nature.com
Pyrazole derivatives are aromatic heterocyclic compounds endowed with multifaceted
applications. In the present study 1, 3, 4-trisubstituted pyrazoles derivatives have been …

Development of potential cathepsin B inhibitors: Synthesis of new bithiazole derivatives, in vitro studies supported with theoretical docking studies

S Yadav, C Vashisth, V Chaudhri, K Singh… - International Journal of …, 2024 - Elsevier
Cysteine cathepsins play a crucial role in cancer, inflammation, and the regulation of
degenerative processes such as apoptosis, making them significant targets in drug …

One-Pot Synthesis of 1,3,5-Trisubstitued Pyrazoles via Immobilized Thermomyces lanuginosus Lipase (TLL) on a Metal–Organic Framework

Z Rangraz, MM Amini, Z Habibi - ACS omega, 2024 - ACS Publications
A regioselective enzyme-catalyzed system is selected for the synthesis of 1, 3, 5-
trisubstituted pyrazole derivatives by adding phenyl hydrazines, nitroolefins, and …

Zinc‐Catalysed (3+2) Cycloaddition of Enaminone with Tosylhydrazide to Synthesise 1H‐Pyrazole via C−N and S−N Bond Cleavage

S Roy, R Chatterjee, R Dandela - Asian Journal of Organic …, 2024 - Wiley Online Library
A novel and practical zinc‐catalysed synthesis of 1H‐pyrazole has been developed. The
one‐pot protocol enables the cycloaddition of enaminone and tosylhydrazide via C− N and …

Advancements in the Synthesis of Triazolopyrimidines

S Singh, R Lakhia, S Yadav, P Devi… - Current Organic …, 2024 - benthamdirect.com
The triazolopyrimidine scaffold indeed holds a prominent place in medicinal chemistry due
to its versatile pharmacological properties. Researchers have explored the scaffold and its …