Biomechanical properties of the pelvic floor and its relation to pelvic floor disorders

AM Ruiz-Zapata, AJ Feola, J Heesakkers… - European Urology …, 2018 - Elsevier
Pelvic organ prolapse and stress urinary incontinence remain a clinical challenge as they
have unclear pathophysiology and suboptimal treatments. These common pelvic floor …

Contractile properties of vaginal tissue

A Huntington, K Donaldson… - Journal of …, 2020 - asmedigitalcollection.asme.org
The vagina is an important organ of the female reproductive system that has been largely
understudied in the field of biomechanics. In recent years, some research has been …

Smooth muscle regional contribution to vaginal wall function

GL Clark, AP Pokutta-Paskaleva… - Interface …, 2019 - royalsocietypublishing.org
Pelvic organ prolapse is characterized as the descent of the pelvic organs into the vaginal
canal. In the USA, there is a 12% lifetime risk for requiring surgical intervention. Although …

Smooth muscle contribution to vaginal viscoelastic response

GL Clark-Patterson, LM Buchanan, BO Ogola… - Journal of the …, 2023 - Elsevier
Smooth muscle cells contribute to the mechanical function of various soft tissues, however,
their contribution to the viscoelastic response when subjected to multiaxial loading remains …

The impact of prolapse mesh on vaginal smooth muscle structure and function

Z Jallah, R Liang, A Feola, W Barone… - … Journal of Obstetrics …, 2016 - Wiley Online Library
Objective To evaluate the impact of prolapse meshes on vaginal smooth muscle structure
(Va SM) and function, and to evaluate these outcomes in the context of the mechanical and …

Strains induced in the vagina by smooth muscle contractions

A Huntington, SD Abramowitch, PA Moalli, R De Vita - Acta biomaterialia, 2021 - Elsevier
The ability of the vagina to contract gives rise to a set of active mechanical properties that
contribute to the complex function of this organ in-vivo. Regional differences in the …

Host reaction to vaginally inserted collagen containing polypropylene implants in sheep

A Feola, M Endo, I Urbankova, J Vlacil… - American Journal of …, 2015 - Elsevier
Objective We aimed to characterize the effect of vaginal or abdominal mesh insertion and of
different collagen augmentation of polypropylene mesh in a sheep model. Outcome …

Anisotropy of the passive and active rat vagina under biaxial loading

A Huntington, E Rizzuto, S Abramowitch… - Annals of Biomedical …, 2019 - Springer
Pelvic organ prolapse, the descent of the pelvic organs from their normal anatomical
position, is a common condition among women that is associated with mechanical …

Feasibility study and design of an automatic system for electronic components disassembly

M Marconi, G Palmieri… - Journal of …, 2019 - asmedigitalcollection.asme.org
The improvement of the waste management efficiency and sustainability in the electronics
sector requires the disassembly and reuse of valuable electronic components, instead of …

Role of fibulin-5 insufficiency and prolapse progression on murine vaginal biomechanical function

GL Clark-Patterson, S Roy, L Desrosiers, LR Knoepp… - Scientific reports, 2021 - nature.com
The vagina plays a critical role in supporting the pelvic organs and loss of support leads to
pelvic organ prolapse. It is unknown what microstructural changes influence prolapse …