Clinical features, diagnosis, and management of enterovirus 71

MH Ooi, SC Wong, P Lewthwaite, MJ Cardosa… - The Lancet …, 2010 - thelancet.com
Although poliomyelitis has been mostly eradicated worldwide, large outbreaks of the related
enterovirus 71 have been seen in Asia-Pacific countries in the past 10 years. This virus …

Slicing and dicing viruses: antiviral RNA interference in mammals

PV Maillard, AG Van der Veen, EZ Poirier… - The EMBO …, 2019 - embopress.org
To protect against the harmful consequences of viral infections, organisms are equipped
with sophisticated antiviral mechanisms, including cell‐intrinsic means to restrict viral …

Cleavage of the adaptor protein TRIF by enterovirus 71 3C inhibits antiviral responses mediated by Toll-like receptor 3

X Lei, Z Sun, X Liu, Q Jin, B He, J Wang - Journal of virology, 2011 - Am Soc Microbiol
ABSTRACT Enterovirus 71 (EV71) causes hand-foot-and-mouth disease and neurological
complications in young children. Although the underlying mechanisms remain obscure …

Cleavage of interferon regulatory factor 7 by enterovirus 71 3C suppresses cellular responses

X Lei, X Xiao, Q Xue, Q Jin, B He, J Wang - Journal of virology, 2013 - Am Soc Microbiol
ABSTRACT Enterovirus 71 (EV71) is a positive-stranded RNA virus which is capable of
inhibiting innate immunity. Among virus-encoded proteins, the 3C protein compromises the …

AAV-CRISPR-Cas13 eliminates human enterovirus and prevents death of infected mice

CT Keng, T Yogarajah, RCH Lee, IBH Muhammad… - …, 2023 - thelancet.com
Background RNA viruses account for many human diseases and pandemic events but are
often not targetable by traditional therapeutics modalities. Here, we demonstrate that adeno …

Antivirals and vaccines for Enterovirus A71

JY Lin, YA Kung, SR Shih - Journal of biomedical science, 2019 - Springer
Abstract Enterovirus A71 (EV-A71) is an important emerging virus posing a threat to children
under five years old. EV-A71 infection in infants or young children can cause hand-foot-and …

Lycorine reduces mortality of human enterovirus 71-infected mice by inhibiting virus replication

J Liu, Y Yang, Y Xu, C Ma, C Qin, L Zhang - Virology journal, 2011 - Springer
Abstract Human enterovirus 71 (EV71) infection causes hand, foot and mouth disease in
children under 6 years old and this infection occasionally induces severe neurological …

Innate immunity and immune evasion by enterovirus 71

PS Pathinayake, ACY Hsu, PAB Wark - Viruses, 2015 - mdpi.com
Enterovirus 71 (EV71) is a major infectious disease affecting millions of people worldwide
and it is the main etiological agent for outbreaks of hand foot and mouth disease (HFMD) …

[HTML][HTML] Pathogenesis study of enterovirus 71 infection in rhesus monkeys

Y Zhang, W Cui, L Liu, J Wang, H Zhao, Y Liao… - Laboratory …, 2011 - Elsevier
Abstract Enterovirus 71 (EV71), a major pathogen that is responsible for causing hand-foot-
and-mouth disease (HFMD) worldwide, is a member of the Human Enterovirus species A …

Enterovirus 71 3C inhibits cytokine expression through cleavage of the TAK1/TAB1/TAB2/TAB3 complex

X Lei, N Han, X Xiao, Q Jin, B He, J Wang - Journal of virology, 2014 - Am Soc Microbiol
ABSTRACT Enterovirus 71 (EV71) causes hand, foot, and mouth disease in young children
and infants. Severe infection with EV71 can lead to various neurological complications or …