FcRγIIA response duality in leishmaniasis

I Hammi, J Giron-Michel, K Akarid, D Arnoult - Microbial Pathogenesis, 2024 - Elsevier
Leishmania is responsible for a neglected tropical disease affecting millions of people
around the world and could potentially spread more due to climate change. This disease not …

Anaplasma phagocytophilum invasin AipA interacts with CD13 to elicit Src kinase signaling that promotes infection

MCH Lind, WA Naimi, TJ Chiarelli, T Sparrer, M Ghosh… - Mbio, 2024 - journals.asm.org
Host-microbe interactions that facilitate entry into mammalian cells are essential for obligate
intracellular bacterial survival and pathogenesis. Anaplasma phagocytophilum is an …

MAPK/ERK activation in macrophages promotes Leishmania internalization and pathogenesis

U Barrie, K Floyd, A Datta, DM Wetzel - Microbes and Infection, 2024 - Elsevier
The obligate intracellular parasite Leishmania binds several receptors to trigger uptake by
phagocytic cells, ultimately resulting in visceral or cutaneous leishmaniasis. A series of …

[HTML][HTML] Using machine learning to dissect host kinases required for Leishmania internalization and development

L Wei, U Barrie, GM Aloisio, FTH Khuong, N Arang… - bioRxiv, 2024 - ncbi.nlm.nih.gov
The Leishmania life cycle alternates between promastigotes, found in the sandfly, and
amastigotes, found in mammals. When an infected sandfly bites a host, promastigotes are …

[HTML][HTML] A Multi-Color Immunofluorescence Assay to Distinguish Intracellular From External Leishmania Parasites

A Datta, U Barrie, DM Wetzel - Bio-protocol, 2024 - ncbi.nlm.nih.gov
Leishmaniasis, a neglected tropical disease, is caused by the intracellular protozoan
parasite Leishmania. Upon its transmission through a sandfly bite, Leishmania binds and …