Aptamer-functionalized nanoparticles in targeted delivery and cancer therapy

Z Fu, J Xiang - International Journal of Molecular Sciences, 2020 - mdpi.com
Using nanoparticles to carry and delivery anticancer drugs holds much promise in cancer
therapy, but nanoparticles per se are lacking specificity. Active targeting, that is, using …

New methods in the diagnosis of cancer and gene therapy of cancer based on nanoparticles

MA Zaimy, N Saffarzadeh, A Mohammadi… - Cancer Gene …, 2017 - nature.com
Cancer is one of the leading cause of death in the world with the prevalence of> 10 million
mortalities annually. Current cancer treatments include surgical intervention, radiation, and …

Core@ shell nanoparticles: greener synthesis using natural plant products

M Khatami, HQ Alijani, MS Nejad, RS Varma - Applied Sciences, 2018 - mdpi.com
Featured Application Greener synthesis and applications of Core-shell nanoparticles.
Abstract Among an array of hybrid nanoparticles, core-shell nanoparticles comprise of two or …

Targeting cancer stem cells to overcome chemoresistance

T Nunes, D Hamdan, C Leboeuf… - International journal of …, 2018 - mdpi.com
Cancers are heterogeneous at the cell level, and the mechanisms leading to cancer
heterogeneity could be clonal evolution or cancer stem cells. Cancer stem cells are resistant …

Delivery strategies in treatments of leukemia

T Ci, W Zhang, Y Qiao, H Li, J Zang, H Li… - Chemical Society …, 2022 - pubs.rsc.org
Leukemia is a hematological malignancy associated with the uncontrolled proliferation of
mutant progenitors, suppressing the production of normal blood cells. Current treatments …

Advances in drug delivery systems for the treatment of acute myeloid leukemia

X Wu, F Wang, X Yang, Y Gong, T Niu, B Chu, Y Qu… - Small, 2024 - Wiley Online Library
Acute myeloid leukemia (AML) is a common and catastrophic hematological neoplasm with
high mortality rates. Conventional therapies, including chemotherapy, hematopoietic stem …

Bacterial Biosynthesis of Gold Nanoparticles Using Salmonella enterica subsp. enterica serovar Typhi Isolated from Blood and Stool Specimens of Patients

SM Mortazavi, M Khatami, I Sharifi, H Heli… - Journal of Cluster …, 2017 - Springer
Salmonella is one of the most common causes of gastroenteritis. In this study, a PCR assay
was developed for the rapid detection of microbial cultures of Salmonella enterica sub …

Stimuli-responsive nanoparticle-assisted immunotherapy: A new weapon against solid tumours

B De Angelis, N Depalo, F Petronella… - Journal of Materials …, 2020 - pubs.rsc.org
Although significant improvements in cancer treatment have led to a longer survival period,
the death rate of patients with solid tumours has not changed during the last decades. Most …

Aptamers and antisense oligonucleotides for diagnosis and treatment of hematological diseases

V Giudice, F Mensitieri, V Izzo, A Filippelli… - International journal of …, 2020 - mdpi.com
Aptamers or chemical antibodies are single-stranded DNA or RNA oligonucleotides that
bind proteins and small molecules with high affinity and specificity by recognizing tertiary or …

The Research Advances of Aptamers in Hematologic Malignancies

Y Liao, S Xiong, Z Ur Rehman, X He, H Peng, J Liu… - Cancers, 2023 - mdpi.com
Simple Summary Aptamer is a targeting tool with many unique advantages, therefore many
experts screened corresponding aptamers in various hematologic malignancies for …